The ventral surface of the rostral medulla oblongata has been suspected since the 1960s to
harbor central respiratory chemoreceptors [ie, acid-activated neurons that regulate breathing …

Maintenance of constant brain pH is critically important to support the activity of individual
neurons, effective communication within the neuronal circuits, and, thus, efficient processing …

The interoceptive homeostatic mechanism that controls breathing, blood gases and acid‐
base balance in response to changes in CO2/H+ is exquisitely sensitive, with convergent …

New Findings What is the topic of this review? Cerebrovascular reactivity to CO2, which is a
principal factor in determining ventilatory responses to CO2 through the role reactivity plays …

The rostral half of the ventrolateral medulla (RVLM) and adjacent ventrolateral retropontine
region (henceforth RVLMRP) have been divided into various sectors by neuroscientists …

An interoceptive homeostatic system monitors levels of CO2/H+ and provides a
proportionate drive to respiratory control networks that adjust lung ventilation to maintain …

Respiratory chemoreceptors regulate breathing in response to changes in tissue CO2/H+.
Blood flow is a fundamental determinant of tissue CO2/H+, yet little is known regarding how …

The retrotrapezoid nucleus (RTN) regulates breathing in a CO2‐and state‐dependent
manner. RTN neurons are glutamatergic and innervate principally the respiratory pattern …

Carbon dioxide (CO2), the major product of metabolism, has a strong impact on cerebral
blood vessels, a phenomenon known as cerebrovascular reactivity. Several vascular risk …

New Findings What is the central question of this study? What is the relationship between
neuroanatomical and functional respiratory changes in an experimental model of …