Introduction Bone is an integral part of the osteoarthritis (OA) process. We conducted a
systematic literature review in order to understand the relationship between non …

Imaging in clinical trials is used to evaluate subject eligibility, and/or efficacy of intervention,
supporting decision making in drug development by ascertaining treatment effects on joint …

The Osteoarthritis Initiative (OAI) is a multicentre, prospective, observational, cohort study of
knee osteoarthritis (OA) that began recruitment in 2004. The OAI provides public access to …

Varus knee deformity is very common, and it can be classified according to the severity and
reducibility of the deformity. Pre-operative planning is mandatory to obtain a good result …

Objectives To assess whether initial or 12–18-month change in magnetic resonance
imaging (MRI) subchondral bone texture is predictive of radiographic knee osteoarthritis …

Objective Magnetic resonance imaging (MRI) texture analysis is a method of analyzing
subchondral bone alterations in osteoarthritis (OA). The objective of this study was to …

With the high prevalence of pediatric obesity there is a need for structured physical activity
during childhood. However, altered tibiofemoral loading during physical activity in obese …

Background Risk prediction algorithms increase understanding of which patients are at
greatest risk of a harmful outcome. Our goal was to create a clinically useful prediction …

Objective Osteoarthritis (OA) is a disease with a substantial public health burden.
Quantitative assessments of periarticular bone may be a biomarker capable of monitoring …

Objectives To determine the feasibility of MRI texture analysis as a method of quantifying
subchondral bone architecture in knee osteoarthritis (OA). Methods Asymptomatic subjects …