Malaria: the past and the present

J Talapko, I Škrlec, T Alebić, M Jukić, A Včev - Microorganisms, 2019 - mdpi.com
Malaria is a severe disease caused by parasites of the genus Plasmodium, which is
transmitted to humans by a bite of an infected female mosquito of the species Anopheles …

Advances in biosensors and optical assays for diagnosis and detection of malaria

KV Ragavan, S Kumar, S Swaraj… - Biosensors and …, 2018 - Elsevier
Vector-borne diseases are a major concern for human health globally, especially malaria in
densely populated, less developed, tropical regions of the world. Malaria causes loss of …

A portable microfluidic Aptamer-Tethered Enzyme Capture (APTEC) biosensor for malaria diagnosis

LA Fraser, AB Kinghorn, RM Dirkzwager… - Biosensors and …, 2018 - Elsevier
There is a critical need for better biosensors for the detection and diagnosis of malaria. We
previously developed a DNA aptamer that recognises the Plasmodium falciparum lactate …

[HTML][HTML] Beyond blood smears: qualification of Plasmodium 18S rRNA as a biomarker for controlled human malaria infections

AM Seilie, M Chang, AE Hanron… - The American journal …, 2019 - ncbi.nlm.nih.gov
18S rRNA is a biomarker that provides an alternative to thick blood smears in controlled
human malaria infection (CHMI) trials. We reviewed data from CHMI trials at non-endemic …

Cost-effectiveness analysis of malaria rapid diagnostic tests: a systematic review

XX Ling, JJ Jin, GD Zhu, WM Wang, YY Cao… - Infectious Diseases of …, 2019 - mednexus.org
Background: Rapid diagnostic tests (RDT) can effectively manage malaria cases and reduce
excess costs brought by misdiagnosis. However, few studies have evaluated the economic …

Malaria infected erythrocyte classification based on a hybrid classifier using microscopic images of thin blood smear

SS Devi, A Roy, J Singha, SA Sheikh… - Multimedia Tools and …, 2018 - Springer
This paper aims to develop the computer assisted malaria infected erythrocyte classification
based on a hybrid classifier. The major issues are feature extraction, optimal feature …

An optimized features selection approach based on Manta Ray Foraging Optimization (MRFO) method for parasite malaria classification

J Amin, M Sharif, GA Mallah… - Frontiers in Public Health, 2022 - frontiersin.org
Malaria is a serious and lethal disease that has been reported by the World Health
Organization (WHO), with an estimated 219 million new cases and 435,000 deaths globally …

Rethinking detection of pre-existing and intervening Plasmodium infections in malaria clinical trials

TJ Owalla, DEB Hergott, AM Seilie, W Staubus… - Frontiers in …, 2022 - frontiersin.org
Pre-existing and intervening low-density Plasmodium infections complicate the conduct of
malaria clinical trials. These infections confound infection detection endpoints, and their …

Clinical determinants of early parasitological response to ACTs in African patients with uncomplicated falciparum malaria: a literature review and meta-analysis of …

… Artemisinin based Combination Therapy (ACT) Africa … - BMC medicine, 2015 - Springer
Abstract Background Artemisinin-resistant Plasmodium falciparum has emerged in the
Greater Mekong sub-region and poses a major global public health threat. Slow parasite …

Noninvasive in vivo photoacoustic detection of malaria with Cytophone in Cameroon

AC Yadem, JN Armstrong, M Sarimollaoglu… - Nature …, 2024 - nature.com
Current malaria diagnostics are invasive, lack sensitivity, and rapid tests are plagued by
deletions in target antigens. Here we introduce the Cytophone, an innovative photoacoustic …