Phenomics: the next challenge

D Houle, DR Govindaraju, S Omholt - Nature reviews genetics, 2010 - nature.com
A key goal of biology is to understand phenotypic characteristics, such as health, disease
and evolutionary fitness. Phenotypic variation is produced through a complex web of …

Systems genetics approaches to understand complex traits

M Civelek, AJ Lusis - Nature Reviews Genetics, 2014 - nature.com
Abstract Systems genetics is an approach to understand the flow of biological information
that underlies complex traits. It uses a range of experimental and statistical methods to …

Growth efficiency, intestinal biology, and nutrient utilization and requirements of black soldier fly (Hermetia illucens) larvae compared to monogastric livestock species …

MM Seyedalmoosavi, M Mielenz, T Veldkamp… - Journal of Animal …, 2022 - Springer
In recent years, interest in the larvae of black soldier fly (BSF)(Hermetia illucens) as a
sustainable protein resource for livestock feed has increased considerably. However …

Gut microbiota dictates the metabolic response of Drosophila to diet

ACN Wong, AJ Dobson… - Journal of Experimental …, 2014 - journals.biologists.com
Animal nutrition is profoundly influenced by the gut microbiota, but knowledge of the scope
and core mechanisms of the underlying animal–microbiota interactions is fragmentary. To …

The genetic differentiation at quantitative trait loci under local adaptation

V Le Corre, A Kremer - Molecular ecology, 2012 - Wiley Online Library
Most adaptive traits are controlled by large number of genes that may all together be the
targets of selection. Adaptation may thus involve multiple but not necessarily substantial …

Association genetics of complex traits in plants

PK Ingvarsson, NR Street - New Phytologist, 2011 - Wiley Online Library
Association mapping is rapidly becoming the main method for dissecting the genetic
architecture of complex traits in plants. Currently most association mapping studies in plants …

Global Diversity Lines–A Five-Continent Reference Panel of Sequenced Drosophila melanogaster Strains

JK Grenier, JR Arguello, MC Moreira… - G3: Genes …, 2015 - academic.oup.com
Reference collections of multiple Drosophila lines with accumulating collections of “omics”
data have proven especially valuable for the study of population genetics and complex trait …

Obesity and Aging in the Drosophila Model

M Gáliková, P Klepsatel - International journal of molecular sciences, 2018 - mdpi.com
Being overweight increases the risk of many metabolic disorders, but how it affects lifespan
is not completely clear. Not all obese people become ill, and the exact mechanism that turns …

Host genetic control of the microbiota mediates the Drosophila nutritional phenotype

JM Chaston, AJ Dobson, PD Newell… - Applied and …, 2016 - Am Soc Microbiol
ABSTRACT A wealth of studies has demonstrated that resident microorganisms (microbiota)
influence the pattern of nutrient allocation to animal protein and energy stores, but it is …

Quantitative Genetics of Food Intake in Drosophila melanogaster

ME Garlapow, W Huang, MT Yarboro, KR Peterson… - PloS one, 2015 - journals.plos.org
Food intake is an essential animal activity, regulated by neural circuits that motivate food
localization, evaluate nutritional content and acceptance or rejection responses through the …