Mechanistic pathogenesis of endothelial dysfunction in diabetic nephropathy and retinopathy

J Yang, Z Liu - Frontiers in endocrinology, 2022 - frontiersin.org
Diabetic nephropathy (DN) and diabetic retinopathy (DR) are microvascular complications of
diabetes. Microvascular endothelial cells are thought to be the major targets of …

Emerging roles of exosomal miRNAs in diabetes mellitus

X He, G Kuang, Y Wu, C Ou - Clinical and translational …, 2021 - Wiley Online Library
Exosomes are small extracellular vesicles 40–160 nm in diameter that are secreted by
almost all cell types. Exosomes can carry diverse cargo including RNA, DNA, lipids …

Exosomal ncRNAs: Novel therapeutic target and biomarker for diabetic complications

YX Xu, SD Pu, X Li, ZW Yu, YT Zhang, XW Tong… - Pharmacological …, 2022 - Elsevier
Exosomes are discoid vesicles with a diameter of 40–160 nm. They are mainly derived from
the multivesicular body formed by the invagination of lysosomal particles in the cell, which …

Roles of exosomes in ocular diseases

J Liu, F Jiang, Y Jiang, Y Wang, Z Li, X Shi… - International journal …, 2020 - Taylor & Francis
Exosomes, nanoscale vesicles with a diameter of 30 to 150 nm, are composed of a lipid
bilayer, protein, and genetic material. Exosomes are secreted by virtually all types of cells in …

Exosomes, extracellular vesicles and the eye

D Rudraprasad, A Rawat, J Joseph - Experimental Eye Research, 2022 - Elsevier
Exosomes are a subset of extracellular vesicles which accommodate a cargo of bioactive
biomolecules that generally includes proteins, nucleic acids, lipids, sugars, and related …

Exosomal non-coding RNAs in angiogenesis: Functions, mechanisms and potential clinical applications

Z Wang, W Tan, B Li, J Zou, Y Li, Y Xiao, Y He… - Heliyon, 2023 - cell.com
Exosomes are extracellular vesicles that can be produced by most cells. Exosomes act as
important intermediaries in intercellular communication, and participate in a variety of …

Effect of ω-3 polyunsaturated fatty acids-derived bioactive lipids on metabolic disorders

J Duan, Y Song, X Zhang, C Wang - Frontiers in physiology, 2021 - frontiersin.org
Arachidonic acid (ARA) is an important ω-6 polyunsaturated fatty acid (PUFA), and
docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA) and n-3 docosapentaenoic acid …

Research progress on the pathogenesis of diabetic retinopathy

H Li, X Liu, H Zhong, J Fang, X Li, R Shi, Q Yu - BMC ophthalmology, 2023 - Springer
Diabetic retinopathy is one of the most common and serious microvascular complications of
diabetes mellitus. There are many factors leading to diabetic retinopathy, and its …

Salivary exosomes in health and disease: future prospects in the eye

A Liu, B Hefley, P Escandon, SE Nicholas… - International journal of …, 2023 - mdpi.com
Exosomes are a group of vesicles that package and transport DNA, RNA, proteins, and
lipids to recipient cells. They can be derived from blood, saliva, urine, and/or other biological …

The correlation between MicroRNAs and diabetic retinopathy

X Zhao, F Ling, G Zhang, N Yu, J Yang… - Frontiers in …, 2022 - frontiersin.org
Micro ribonucleic acids (miRNAs), as a category of post-transcriptional gene inhibitors, have
a wide range of biological functions, are involved in many pathological processes, and are …