Chloroquine (CHQ) is a cheap, relatively well tolerated drug initially developed for the
treatment of malaria in the 1930s. CHQ has, however, since accrued a plethora of uses in …

The effect of chloroquine (CHQ) administration on antioxidant enzymes in rat liver and
kidney was studied. Male Sprague–Dawley rats were administered 20 mg/kg CHQ once a …

Primaquine and chloroquine are used for the treatment of malaria; evidence from the
literature suggests that these drugs may induce oxidative stress. In this study we …

The aim of the present study was to investigate the suitability of amidated pectin matrix patch
for transdermal chloroquine delivery in an effort to mask the bitter taste when orally …

Background Acute kidney injury (AKI) still remains an unresolved problem in
pharmacotherapy and renal inflammation is a major factor in its development. Chloroquine …

The aim of the present study was to delay the release of chloroquine to distal parts of the
gastrointestinal tract by using a multiparticulate hydrogel formulation. Amidated pectin …

The effects of 3 consecutive days of oral chloroquine (1 mg/100 g body weight) on kidney
function and blood pressure were studied in male Sprague—Dawley rats that were …

We have previously reported that chloroquine administration increases plasma vasopressin
concentration and urinary sodium excretion in Sprague-Dawley rats. Because chloroquine …

This study investigated the effects of long-term chloroquine and ethanol administration on
renal fluid and electrolyte handling and kidney structure. Male Sprague–Dawley rats were …

We postulated that chloroquine increases plasma arginine vasopressin (AVP)
concentrations thus altering renal Na+ clearance. Therefore, we studied a relationship …