The coupling of waves between the piezoelectric generators, detectors, and propagating
media is challenging due to mismatch in the acoustic properties. The mismatch leads to the …

Therapeutic ultrasound strategies that harness the mechanical activity of cavitation nuclei for
beneficial tissue bio-effects are actively under development. The mechanical oscillations of …

Optogenetics has revolutionized neuroscience understanding by allowing spatiotemporal
control over cell-type specific neurons in neural circuits. However, the sluggish development …

Histotripsy is a focused ultrasound therapy for non-invasive tissue ablation. Unlike thermally
ablative forms of therapeutic ultrasound, histotripsy relies on the mechanical action of …

High intensity focused ultrasound (HIFU) is gaining rapid clinical acceptance as a treatment
modality enabling non-invasive tissue heating and ablation for numerous applications. HIFU …

Ultrasonic biophysics is the study of mechanisms responsible for how ultrasound and
biological materials interact. Ultrasound-induced bioeffect or risk studies focus on issues …

Therapeutic applications of ultrasound predate its use in imaging. A range of biological
effects can be induced by ultrasound, depending on the exposure levels used. At low levels …

Histotripsy is a therapy that focuses short-duration, high-amplitude pulses of ultrasound to
incite a localized cavitation cloud that mechanically breaks down tissue. To investigate the …

This paper is based on material presented at the start of a Health Protection Agency meeting
on ultrasound and infrasound. In answering the question 'what is ultrasound?', it shows that …

Therapeutic ultrasound is an emerging field with many medical applications. High intensity
focused ultrasound (HIFU) provides the ability to localize the deposition of acoustic energy …