Intermittent Oxygen Fasting and Digital Technologies: from Antistress and Hormones Regulation to Wellbeing, Bliss and Higher Mental States

A Drigas, E Mitsea, C Skianis - Technium BioChemMed, 2022 - techniumscience.com
Low oxygen breathing has been the subject of considerable research in recent years. The
present review aims to determine the physiological and neuropsychological benefits of low …

[HTML][HTML] The interplay of hypoxic and mental stress: Implications for anxiety and depressive disorders

J Burtscher, M Niedermeier, K Hüfner… - Neuroscience & …, 2022 - Elsevier
Adequate oxygen supply is essential for the human brain to meet its high energy demands.
Therefore, elaborate molecular and systemic mechanism are in place to enable adaptation …

Salidroside intensifies mitochondrial function of CoCl2-damaged HT22 cells by stimulating PI3K-AKT-MAPK signaling pathway

Y Hou, Y Zhang, S Jiang, N Xie, Y Zhang, X Meng… - Phytomedicine, 2023 - Elsevier
Abstract Background Salidroside (Sal), an active component from Rhodiola crenulata, has
been confirmed to exert neuroprotective effects against hypoxia. However, its molecular …

[HTML][HTML] Erythropoietin re-wires cognition-associated transcriptional networks

M Singh, Y Zhao, VD Gastaldi, SM Wojcik… - Nature …, 2023 - nature.com
Recombinant human erythropoietin (rhEPO) has potent procognitive effects, likely
hematopoiesis-independent, but underlying mechanisms and physiological role of brain …

Ketogenic diet uncovers differential metabolic plasticity of brain cells

T Düking, L Spieth, SA Berghoff, L Piepkorn… - Science …, 2022 - science.org
To maintain homeostasis, the body, including the brain, reprograms its metabolism in
response to altered nutrition or disease. However, the consequences of these challenges for …

[HTML][HTML] Sphingolipids and impaired hypoxic stress responses in Huntington disease

J Burtscher, G Pepe, N Maharjan, N Riguet… - Progress in lipid …, 2023 - Elsevier
Huntington disease (HD) is a debilitating, currently incurable disease. Protein aggregation
and metabolic deficits are pathological hallmarks but their link to neurodegeneration and …

[HTML][HTML] Introducing the brain erythropoietin circle to explain adaptive brain hardware upgrade and improved performance

H Ehrenreich, LF Garcia-Agudo… - Molecular …, 2022 - nature.com
Preface Executive functions, learning, attention, and processing speed are imperative facets
of cognitive performance, affected in neuropsychiatric disorders. In clinical studies on …

Exploiting moderate hypoxia to benefit patients with brain disease: Molecular mechanisms and translational research in progress

H Ehrenreich, M Gassmann, L Poustka… - …, 2023 - mednexus.org
Hypoxia is increasingly recognized as an important physiological driving force. A specific
transcriptional program, induced by a decrease in oxygen (O2) availability, for example …

[HTML][HTML] Pentad: A reproducible cytoarchitectonic protocol and its application to parcellation of the human hippocampus

EM Williams, EW Rosenblum, N Pihlstrom… - Frontiers in …, 2023 - frontiersin.org
Introduction The hippocampus is integral for learning and memory and is targeted by
multiple diseases. Neuroimaging approaches frequently use hippocampal subfield volumes …

miRNA cargo in circulating vesicles from neurons is altered in individuals with schizophrenia and associated with severe disease

MM Barnett, WR Reay, MP Geaghan… - Science …, 2023 - science.org
While RNA expression appears to be altered in several brain disorders, the constraints of
postmortem analysis make it impractical for well-powered population studies and biomarker …