Cancer cells have the ability of dysregulation and autonomous proliferation due to
unchecked production of definite molecules. These molecules are involved in the cell growth …

There are over 100 commercially available drugs for the handling of cancer, but only a
handful of them have high specificity, leading to a variety of side effects. The past few …

In this study, we designed and synthesized a number of novel pyrido [2, 3-d] pyrimidine-
thiazolidine-1, 2, 3-triazole derivatives and investigated them in vitro for their inhibitory …

Herein, we synthesized some new fused [1, 2, 3] triazolo-pyrrolo [1, 2-a] pyrido [4, 3-d]
pyrimidines via click chemistry followed by carbon-carbon bond coupling as key approach …

Synthetic chemists have organized easy and effective ways for perfect synthesis in response
to the requirement for scaffolds that are crucial for medical applications. To investigate the …

The CuI promoted one‐pot multi‐component synthesis of new fused [1, 2, 3] triazolo [5, 1‐a]
isoquinoline derivatives (4 a–4 h, 8 a–8 f & 9 a–9 f) without isolating unsafe azides and their …

A one‐step procedure for the synthesis of new fused Benzo [d] thiazolo‐1, 2, 3‐triazoles (3 a–
3 h and 4 a–4 h) in good yields using sulfonylazides (2) and iodoalkyne (1) through from the …

Cancer is a wide collection of diseases and among the numerous pathways involved in
cancer pathogenesis, pathway involving epidermal growth factor receptor (EGFR) is one of …

A general strategy was developed for the synthesis of new fully decorated sulfonyl1, 2, 3-
triazolyl pyrimidines (6a–6j and 8a–8f) from 2-((6-methyl-2-(methylsulfonyl) pyrimidin-4-yl) …

A general strategy was developed for the synthesis of new fully decorated sulfonyl1, 2, 3‐
triazolyl imidazoles from β‐ketosulfones and several aryl sulfonyl azides using the …