Vitamin D derivatives in acute myeloid leukemia: The matter of selecting the right targets
E Marcinkowska - Nutrients, 2022 - mdpi.com
Acute myeloid leukemia (AML) is an aggressive and often fatal hematopoietic malignancy. A
very attractive way to treat myeloid leukemia, called “differentiation therapy”, was proposed …
very attractive way to treat myeloid leukemia, called “differentiation therapy”, was proposed …
Lithocholic acid amides as potent vitamin D receptor agonists
A Yoshihara, H Kawasaki, H Masuno, K Takada… - Biomolecules, 2022 - mdpi.com
1α, 25-Dihydroxyvitamin D3 [1α, 25 (OH) 2D3, 1] is an active form of vitamin D3 and
regulates various biological phenomena, including calcium and phosphate homeostasis …
regulates various biological phenomena, including calcium and phosphate homeostasis …
Design, synthesis and evaluation of side-chain hydroxylated derivatives of lithocholic acid as potent agonists of the vitamin D receptor (VDR)
CM González, S Gaikwad, G Lasanta, J Loureiro… - Bioorganic …, 2021 - Elsevier
A high number of biologically active and low-calcemic secosteroidal ligands of the vitamin D
receptor (VDR) have been developed, some of which are already used clinically although …
receptor (VDR) have been developed, some of which are already used clinically although …
Design and synthesis of vitamin D analogs
MA Maestro - Feldman and Pike's Vitamin D, 2024 - Elsevier
Design and synthesis of vitamin D analogs - ScienceDirect Skip to main contentSkip to article
Elsevier logo Journals & Books Search RegisterSign in View PDF Download full book Search …
Elsevier logo Journals & Books Search RegisterSign in View PDF Download full book Search …
Antiproliferative and immunoregulatory actions of vitamin D derivatives on hematological malignancies: control of differentiation, proliferation, and cell death
GP Studzinski, E Gocek, E Marcinkowska… - Feldman and Pike's …, 2024 - Elsevier
The physiological form of vitamin D, 1, 25-dihydroxyvitamin D 3 (1, 25 (OH) 2 D 3), has a role
in normal hematopoiesis, enhancing monocyte–macrophage differentiation. The focus in …
in normal hematopoiesis, enhancing monocyte–macrophage differentiation. The focus in …
Structural basis for ligand activity in vitamin D receptor
AY Belorusova, N Rochel - Vitamin D, 2018 - Elsevier
The vitamin D receptor (VDR) and its natural ligand, 1α, 25-dihydroxyvitamin D 3 (1, 25 (OH)
2 D 3, or calcitriol), regulate mineral homeostasis and metabolism, cell growth …
2 D 3, or calcitriol), regulate mineral homeostasis and metabolism, cell growth …
Exploring Coumarin-Thiazole Scaffolds: Synthesis, Structure-Activity Relationship, and Molecular Insights into Anti-Tubercular Activity
SA Shaikh, SR Labhade, RR Kale, AS Jadhav… - … , and Molecular Insights … - papers.ssrn.com
Tuberculosis remains a global health threat, with rising infection rates and fatalities. Herein,
an efficient and smart approach for design and synthesis of a novel series of 2-(4-(((2-oxo …
an efficient and smart approach for design and synthesis of a novel series of 2-(4-(((2-oxo …