The role of circulating biomarkers in peripheral arterial disease
G Saenz-Pipaon, E Martinez-Aguilar, J Orbe… - International Journal of …, 2021 - mdpi.com
Peripheral arterial disease (PAD) of the lower extremities is a chronic illness predominantly
of atherosclerotic aetiology, associated to traditional cardiovascular (CV) risk factors. It is …
of atherosclerotic aetiology, associated to traditional cardiovascular (CV) risk factors. It is …
The role of neutrophils in lower limb peripheral artery disease: state of the art and future perspectives
G Buso, E Faggin, N Rosenblatt-Velin… - International Journal of …, 2023 - mdpi.com
In recent years, increasing attention has been paid to the role of neutrophils in
cardiovascular (CV) disease (CVD) with evidence supporting their role in the initiation …
cardiovascular (CV) disease (CVD) with evidence supporting their role in the initiation …
Prdm16 supports arterial flow recovery by maintaining endothelial function
S Craps, J Van Wauwe, S De Moudt… - Circulation …, 2021 - Am Heart Assoc
Rationale: Understanding the mechanisms that regulate arterial flow recovery is important to
design treatment options for peripheral artery disease patients ineligible for invasive …
design treatment options for peripheral artery disease patients ineligible for invasive …
Ionizing radiation induces BH4 deficiency by downregulating GTP-cyclohydrolase 1, a novel target for preventing and treating radiation enteritis
T Yan, T Zhang, W Mu, Y Qi, S Guo, N Hu… - Biochemical …, 2020 - Elsevier
Radiation enteritis (RE) is a common side effect after radiotherapy for abdominal cancer. RE
pathogenesis is complicated, with no drugs available for prevention or treatments. Intestinal …
pathogenesis is complicated, with no drugs available for prevention or treatments. Intestinal …
Exposure of endothelium to biomimetic flow waveforms yields identification of miR-199a-5p as a potent regulator of arteriogenesis
Arteriogenesis, the growth of endogenous collateral arteries bypassing arterial occlusion (s),
is a fundamental shear stress-induced adaptation with implications for treating peripheral …
is a fundamental shear stress-induced adaptation with implications for treating peripheral …
Quantifying the vascular response to ischemia with speckle variance optical coherence tomography
Longitudinal monitoring techniques for preclinical models of vascular remodeling are critical
to the development of new therapies for pathological conditions such as ischemia and …
to the development of new therapies for pathological conditions such as ischemia and …
Epigenetic regulators of the revascularization response to chronic arterial occlusion
Peripheral arterial disease (PAD) is the leading cause of lower limb amputation and
estimated to affect over 202 million people worldwide. PAD is caused by atherosclerotic …
estimated to affect over 202 million people worldwide. PAD is caused by atherosclerotic …
Endothelial-specific EphA4 negatively regulates native pial collateral formation and re-perfusion following hindlimb ischemia
B Okyere, K Giridhar, A Hazy, M Chen, D Keimig… - PLoS …, 2016 - journals.plos.org
Leptomeningeal anastomoses play a critical role in regulating vascular re-perfusion
following obstruction, however, the mechanisms regulating their development remains …
following obstruction, however, the mechanisms regulating their development remains …
Dynamic multiscale regulation of perfusion recovery in experimental peripheral arterial disease: a mechanistic computational model
In peripheral arterial disease (PAD), the degree of endogenous capacity to modulate
revascularization of limb muscle is central to the management of leg ischemia. To …
revascularization of limb muscle is central to the management of leg ischemia. To …
MicroRNA-146a Regulates Perfusion Recovery in Response to Arterial Occlusion via Arteriogenesis
JL Heuslein, SP McDonnell, J Song… - … in Bioengineering and …, 2018 - frontiersin.org
The growth of endogenous collateral arteries that bypass arterial occlusion (s), or
arteriogenesis, is a fundamental shear stress-induced adaptation with implications for …
arteriogenesis, is a fundamental shear stress-induced adaptation with implications for …