Fundamental biological features of spaceflight: advancing the field to enable deep-space exploration
Research on astronaut health and model organisms have revealed six features of
spaceflight biology that guide our current understanding of fundamental molecular changes …
spaceflight biology that guide our current understanding of fundamental molecular changes …
Understanding the complexities and changes of the astronaut microbiome for successful long-duration space missions
D Tesei, A Jewczynko, AM Lynch, C Urbaniak - Life, 2022 - mdpi.com
During space missions, astronauts are faced with a variety of challenges that are unique to
spaceflight and that have been known to cause physiological changes in humans over a …
spaceflight and that have been known to cause physiological changes in humans over a …
Spatial multi-omics of human skin reveals KRAS and inflammatory responses to spaceflight
Spaceflight can change metabolic, immunological, and biological homeostasis and cause
skin rashes and irritation, yet the molecular basis remains unclear. To investigate the impact …
skin rashes and irritation, yet the molecular basis remains unclear. To investigate the impact …
Longitudinal multi-omics analysis of host microbiome architecture and immune responses during short-term spaceflight
Maintenance of astronaut health during spaceflight will require monitoring and potentially
modulating their microbiomes. However, documenting microbial shifts during spaceflight has …
modulating their microbiomes. However, documenting microbial shifts during spaceflight has …
Collection of biospecimens from the inspiration4 mission establishes the standards for the space omics and medical atlas (SOMA)
Abstract The SpaceX Inspiration4 mission provided a unique opportunity to study the impact
of spaceflight on the human body. Biospecimen samples were collected from four crew …
of spaceflight on the human body. Biospecimen samples were collected from four crew …
Real-time culture-independent microbial profiling onboard the international space station using nanopore sequencing
For the past two decades, microbial monitoring of the International Space Station (ISS) has
relied on culture-dependent methods that require return to Earth for analysis. This has a …
relied on culture-dependent methods that require return to Earth for analysis. This has a …
Investigation of spaceflight induced changes to astronaut microbiomes
MD Morrison, JB Thissen, F Karouia, S Mehta… - Frontiers in …, 2021 - frontiersin.org
The International Space Station (ISS) is a uniquely enclosed environment that has been
continuously occupied for the last two decades. Throughout its operation, protecting the …
continuously occupied for the last two decades. Throughout its operation, protecting the …
The human microbiome in space: parallels between Earth-based dysbiosis, implications for long-duration spaceflight, and possible mitigation strategies
S Etlin, J Rose, L Bielski, C Walter… - Clinical Microbiology …, 2024 - journals.asm.org
The human microbiota encompasses the diverse communities of microorganisms that reside
in, on, and around various parts of the human body, such as the skin, nasal passages, and …
in, on, and around various parts of the human body, such as the skin, nasal passages, and …
The indoors microbiome and human health
JA Gilbert, EM Hartmann - Nature Reviews Microbiology, 2024 - nature.com
Indoor environments serve as habitat for humans and are replete with various reservoirs and
niches for microorganisms. Microorganisms enter indoor spaces with their human and non …
niches for microorganisms. Microorganisms enter indoor spaces with their human and non …
Microbial Tracking-2, a metagenomics analysis of bacteria and fungi onboard the International Space Station
C Urbaniak, MD Morrison, JB Thissen, F Karouia… - Microbiome, 2022 - Springer
Abstract Background The International Space Station (ISS) is a unique and complex built
environment with the ISS surface microbiome originating from crew and cargo or from life …
environment with the ISS surface microbiome originating from crew and cargo or from life …