Replication and single-cycle delivery of SARS-CoV-2 replicons

I Ricardo-Lax, JM Luna, TTN Thao, J Le Pen, Y Yu… - Science, 2021 - science.org
Molecular virology tools are critical for basic studies of the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) and for developing new therapeutics. Experimental …

Sensitive lateral flow immunoassay based on specific peptide and superior oxidase mimics with a universal dual-mode significant signal amplification

T Dong, X Zhang, J Yuan, Z Lin, P Yin, H Yu… - Analytical …, 2023 - ACS Publications
Rapid and sensitive antigen detection using a lateral flow immunoassay (LFIA) is crucial for
diagnosing infectious diseases due to its simplicity, speed, and user-friendly features …

Recent Progress in Phage‐Based Nanoplatforms for Tumor Therapy

XT Li, SY Peng, SM Feng, TY Bao, SZ Li, SY Li - Small, 2024 - Wiley Online Library
Nanodrug delivery systems have demonstrated a great potential for tumor therapy with the
development of nanotechnology. Nonetheless, traditional drug delivery systems are faced …

Pseudoviruses, a safer toolbox for vaccine development against enveloped viruses

SR Thimmiraju, JT Kimata, J Pollet - Expert Review of Vaccines, 2024 - Taylor & Francis
Introduction Pseudoviruses are recombinant, replication-incompetent, viral particles
designed to mimic the surface characteristics of native enveloped viruses. They are a safer …

Borneol ester derivatives as entry inhibitors of a wide spectrum of SARS-CoV-2 viruses

OI Yarovaya, DN Shcherbakov, SS Borisevich… - Viruses, 2022 - mdpi.com
In the present work we studied the antiviral activity of the home library of monoterpenoid
derivatives using the pseudoviral systems of our development, which have glycoproteins of …

Amyloid precursor protein facilitates SARS-CoV-2 virus entry into cells and enhances amyloid-β-associated pathology in APP/PS1 mouse model of Alzheimer's …

J Chen, J Chen, Z Lei, F Zhang, LH Zeng, X Wu… - Translational …, 2023 - nature.com
Although there are indications of a trend towards less severe acute respiratory symptoms
and a decline in overall lethality from the novel Coronavirus Disease 2019 (COVID-19) …

Luteolin inhibits spike protein of severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) binding to angiotensin‐converting enzyme 2

J Zhu, H Yan, M Shi, M Zhang, J Lu… - Phytotherapy …, 2023 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) causes coronavirus
disease 2019 (COVID‐19), a respiratory illness that poses a serious threat to global public …

A pseudovirus-based platform to measure neutralizing antibodies in Mexico using SARS-CoV-2 as proof-of-concept

JA Cruz-Cardenas, M Gutierrez, A López-Arredondo… - Scientific Reports, 2022 - nature.com
The gold-standard method to evaluate a functional antiviral immune response is to titer
neutralizing antibodies (NAbs) against a viral pathogen. This is historically performed using …

Characterization and discrimination of spike protein in SARS‐CoV‐2 virus‐like particles via surface‐enhanced Raman spectroscopy

M Akdeniz, Z Al‐Shaebi, M Altunbek… - Biotechnology …, 2024 - Wiley Online Library
Non‐infectious virus‐like particles (VLPs) are excellent structures for development of many
biomedical applications such as drug delivery systems, vaccine production platforms, and …

Development of a cell-based SARS-CoV-2 pseudovirus neutralization assay using imaging and flow cytometry analysis

JR Izac, EJ Kwee, L Tian, E Elsheikh… - International Journal of …, 2023 - mdpi.com
COVID-19 is an ongoing, global pandemic caused by the novel, highly infectious SARS-CoV-
2 virus. Efforts to mitigate the effects of SARS-CoV-2, such as mass vaccination and …