Diabetic wound-healing science

JL Burgess, WA Wyant, B Abdo Abujamra, RS Kirsner… - Medicina, 2021 - mdpi.com
Diabetes mellitus is an increasingly prevalent chronic metabolic disease characterized by
prolonged hyperglycemia that leads to long-term health consequences. It is estimated that …

Association of glycemic indices (hyperglycemia, glucose variability, and hypoglycemia) with oxidative stress and diabetic complications

E Papachristoforou, V Lambadiari… - Journal of diabetes …, 2020 - Wiley Online Library
Oxidative stress (OS) is defined as a disturbance in the prooxidant‐antioxidant balance of
the cell, in favor of the former, which results in the antioxidant capacity of the cell to be …

Pathophysiology of peripheral arterial disease in diabetes mellitus: 糖尿病周围动脉疾病的病理生理机制

S Yang, L Zhu, R Han, L Sun, J Li, J Dou - Journal of diabetes, 2017 - Wiley Online Library
Peripheral arterial disease (PAD) increases the risk of lower extremity amputation. It is also
an independent predictor of cardiovascular and cerebrovascular ischemic events, affecting …

Advances of hydrogel dressings in diabetic wounds

H Wang, Z Xu, M Zhao, G Liu, J Wu - Biomaterials science, 2021 - pubs.rsc.org
Currently, the treatment and care of diabetic wounds, which generally possess the
characteristics of a high amputation rate, high recurrence rate and high mortality, has …

Diabetes and wound angiogenesis

UA Okonkwo, LA DiPietro - International journal of molecular sciences, 2017 - mdpi.com
Diabetes Mellitus Type II (DM2) is a growing international health concern with no end in
sight. Complications of DM2 involve a myriad of comorbidities including the serious …

Hyperbaric oxygen potentiates diabetic wound healing by promoting fibroblast cell proliferation and endothelial cell angiogenesis

X Huang, P Liang, B Jiang, P Zhang, W Yu, M Duan… - Life sciences, 2020 - Elsevier
Background Diabetic foot ulcer (DFU), one of the diabetic complications, brings high burden
to diabetic patients. Hyperbaric oxygen therapy (HBOT) has been proven to be an effective …

Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays

SA Bustin - Journal of molecular endocrinology, 2000 - jme.bioscientifica.com
To investigate whether the tumor suppressor gene PTEN affects the activity of the androgen
receptor (AR), we monitored the expression of the apoptotic gene HA-Bax (inserted in an …

Glucose variability: how does it work?

VV Klimontov, OV Saik, AI Korbut - International journal of molecular …, 2021 - mdpi.com
A growing body of evidence points to the role of glucose variability (GV) in the development
of the microvascular and macrovascular complications of diabetes. In this review, we …

Oscillating glucose is more deleterious to endothelial function and oxidative stress than mean glucose in normal and type 2 diabetic patients

A Ceriello, K Esposito, L Piconi, MA Ihnat, JE Thorpe… - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVE—To explore the possibility that oscillating glucose may outweigh A1C levels in
determining the risk for cardiovascular diabetes complications. RESEARCH DESIGN AND …

Hsp20-mediated activation of exosome biogenesis in cardiomyocytes improves cardiac function and angiogenesis in diabetic mice

X Wang, H Gu, W Huang, J Peng, Y Li, L Yang… - Diabetes, 2016 - Am Diabetes Assoc
Decreased heat shock protein (Hsp) expression in type 1 and type 2 diabetes has been
implicated as a primary factor contributing to diabetes-induced organ damage. We recently …