Abstract Gram-positive (G+) bacterial infection is a great burden to both healthcare and
community medical resources. As a result of the increasing prevalence of multidrug-resistant …

Due to the global emergence of antibiotic resistance, there has been an increase in
research surrounding endolysins as an alternative therapeutic. Endolysins are phage …

There is growing concern about the emergence of bacterial strains showing resistance to all
classes of antibiotics commonly used in human medicine. Despite the broad range of …

Peptidoglycan degrading enzymes are of increasing interest as antibacterial agents,
especially against multi-drug resistant pathogens. Herein we present a review about the …

Lower respiratory tract infections and tuberculosis are responsible for the death of about 4.5
million people each year and are the main causes of mortality in children under 5 years of …

Appearance of pathogenic bacteria resistant to most, if not all, known antibiotics is currently
one of the most significant medical problems. Therefore, development of novel antibacterial …

One of the possible solutions for the current antibiotic resistance crisis may be found in
(often bacteriophage-derived) peptidoglycan hydrolases. The first clinical trials of these …

Bacteriophages (phages) or bacterial viruses have been proposed as natural antimicrobial
agents to fight against antibiotic-resistant bacteria associated with human infections …

Abstract Changes in the gut microbiome have pivotal roles in the pathogenesis of acute graft-
versus-host disease (aGVHD) after allogenic haematopoietic cell transplantation (allo …

The global emergence of multidrug-resistant pathogens is shaping the current dogma
regarding the use of antibiotherapy. Many bacteria have evolved to become resistant to …