Vitamin A (all-trans-retinol) is the parent compound of a family of natural and synthetic
compounds, the retinoids. Retinoids regulate gene transcription in numerous cells and …

Dopaminergic neurons located in the ventral mesodiencephalon are essential for the control
of voluntary movement and the regulation of emotion, and are severely affected in …

The Wnts are a family of glycoproteins that regulate cell proliferation, fate decisions, and
differentiation. In our study, we examined the contribution of Wnts to the development of …

The specification of neurotransmitter phenotype is an important aspect of neuronal fate
determination. Substantial progress has been made in uncovering key extracellular signals …

Dopaminergic neurons in the mammalian brain have received substantial attention in the
past given their fundamental role in several body functions and behaviours. The largest …

Antisense (AS) transcripts are RNA molecules that are transcribed from the opposite strand
to sense (S) genes forming S/AS pairs. The most prominent configuration is when a lncRNA …

Autophagy has been shown to be critically associated with the central mechanisms
underlying Parkinson's disease (PD), while the mechanisms contributing to the imbalance of …

The molecular mechanisms regulating endothelial cell activation and vascular smooth
muscle cell proliferation are critical in the pathological processes underlying atherosclerosis …

Because of their unique attributes of plasticity and accessibility, bone marrow-derived
mesenchymal stem cells (MSCs) may find use for therapy of neurodegenerative disorders …

Nurr1, a transcription factor belonging to the nuclear receptor family, is essential for the
generation of midbrain dopamine (DA) cells during embryonic development. Nurr1 …