Supramolecular prodrugs based on host–guest interactions

WC Geng, JL Sessler, DS Guo - Chemical Society Reviews, 2020 - pubs.rsc.org
Classic prodrug strategies rely on covalent modification of active drugs to provide systems
with superior pharmacokinetic properties than the parent drug and facilitate administration …

Biomedical applications of calixarenes: state of the art and perspectives

YC Pan, XY Hu, DS Guo - Angewandte Chemie International …, 2021 - Wiley Online Library
Calixarenes (CAs), representing the third generation of supramolecular hosts and one of the
most widely studied macrocyclic scaffolds, offer (almost) unlimited structure and application …

Supramolecular Chemistry of p-Sulfonatocalix[n]arenes and Its Biological Applications

DS Guo, Y Liu - Accounts of chemical research, 2014 - ACS Publications
Conspectus Developments in macrocyclic chemistry have led to supramolecular chemistry,
a field that has attracted increasing attention among researchers in various disciplines …

[HTML][HTML] Host-guest chemistry in supramolecular theranostics

G Yu, X Chen - Theranostics, 2019 - ncbi.nlm.nih.gov
Macrocyclic hosts, such as cyclodextrins, calixarenes, cucurbiturils, and pillararenes, exhibit
unparalleled advantages in disease diagnosis and therapy over the past years by fully …

Pillar [6] arene/paraquat molecular recognition in water: high binding strength, pH-responsiveness, and application in controllable self-assembly, controlled release …

G Yu, X Zhou, Z Zhang, C Han, Z Mao… - Journal of the …, 2012 - ACS Publications
The complexation between a water-soluble pillar [6] arene (WP6) and paraquat (G1) in
water was investigated. They could form a stable 1: 1 [2] pseudorotaxane with an extremely …

Supramolecular hosts as in vivo sequestration agents for pharmaceuticals and toxins

CL Deng, SL Murkli, LD Isaacs - Chemical Society Reviews, 2020 - pubs.rsc.org
Pharmaceutical agents, drugs of abuse, and toxic substances have a large impact, positive
and negative, on modern society. Efforts to mitigate the side effects of pharmaceuticals and …

Cholinesterase-responsive supramolecular vesicle

DS Guo, K Wang, YX Wang, Y Liu - Journal of the American …, 2012 - ACS Publications
Enzyme-responsive, amphiphilic self-assembly represents one of the increasingly significant
topics in biomaterials research and finds feasible applications to the controlled release of …

Progress in host–guest macrocycle/pesticide research: Recognition, detection, release and application

P hui Shan, J hang Hu, M Liu, Z Tao, X Xiao… - Coordination Chemistry …, 2022 - Elsevier
Macrocyclic compounds are formed via a series of cyclic oligomers possessing repeating
units, and classical examples include cyclodextrins, calix [n] arenes, cucurbit [n] urils and …

Near-infrared light-responsive supramolecular nanovalve based on mesoporous silica-coated gold nanorods

H Li, LL Tan, P Jia, QL Li, YL Sun, J Zhang… - Chemical …, 2014 - pubs.rsc.org
We constructed a novel cancer theranostic hybrid platform, based on mesoporous silica-
coated gold nanorods (AuNR@ MSN) gated by sulfonatocalix [4] arene (SC [4] A) switches …

Multistimuli Responsive Supramolecular Vesicles Based on the Recognition of p-Sulfonatocalixarene and its Controllable Release of Doxorubicin

K Wang, DS Guo, X Wang, Y Liu - Acs Nano, 2011 - ACS Publications
We report the novel construction of nanosupramolecular binary vesicles based on host−
guest complex formation between p-sulfonatocalix [4] arene and asymmetric viologen, which …