RNA modifications have recently emerged as critical posttranscriptional regulators of gene
expression programmes. Significant advances have been made in understanding the …

Cancer is one of the major diseases threatening human life and health worldwide.
Epigenetic modification refers to heritable changes in the genetic material without any …

The biosynthesis of ribosomes is a complex process that requires the coordinated action of
many factors and a huge energy investment from the cell. Ribosomes are essential for …

Although cancer was originally considered a disease driven only by genetic mutations, it has
now been proven that it is also an epigenetic disease driven by DNA hypermethylation …

Background RNA-binding proteins (RBPs) play important roles in cellular homeostasis by
controlling gene expression at the post-transcriptional level. Results We explore the …

RNA modifications are dynamic and reversible chemical modifications on substrate RNA
that are regulated by specific modifying enzymes. They play important roles in the regulation …

Background Qualitative alterations or abnormal expression of microRNAs (miRNAs) in colon
cancer have mainly been demonstrated in primary tumors. Poorly overlapping sets of …

In contrast to the amazing exponential growth in knowledge related to long non-coding
RNAs (lncRNAs) involved in cell homeostasis or dysregulated pathological states, little is …

Pseudouridine is the most abundant modification found in RNA. Today, thanks to next-
generation sequencing techniques used in the detection of RNA modifications …

Hepatocellular carcinoma (HCC) is a highly mortal type of primary liver cancer. Abnormal
epigenetic modifications are present in HCC, and RNA modification is dynamic and …