Living cells continually generate reactive oxygen species (ROS) through the respiratory
chain during energetic metabolism. ROS at low or moderate concentration can play …

Chemotherapy is a life‐saving treatment for cancer patients, but also causes long‐term
cognitive impairment, or “chemobrain”, in survivors. However, several challenges, including …

Activity-dependent myelination is thought to contribute to adaptive neurological function.
However, the mechanisms by which activity regulates myelination and the extent to which …

Many cancer patients treated with chemotherapy develop chemotherapy-induced cognitive
impairment (CICI), often referred to as chemo-brain, which manifest during or post-treatment …

The purpose of this review is to summarize the current literature on the effects of cancer
treatment–related cognitive difficulties, with a focus on the effects of chemotherapy …

A subgroup of patients with breast cancer suffers from mild cognitive impairment after
chemotherapy. To uncover the neural substrate of these mental complaints, we examined …

For some cancer survivors chemotherapy treatment is associated with lasting cognitive
impairment, long after treatment cessation. Several candidate mechanisms have been …

Since the first clinical trials conducted after World War II, chemotherapeutic drugs have been
extensively used in the clinic as the main cancer treatment either alone or as an adjuvant …

A wide range of cognitive deficits, including memory loss associated with hippocampal
dysfunction, have been widely reported in cancer survivors who received chemotherapy …

Rationale Chemotherapy-induced cognitive impairment (CICI), chemobrain, and chemofog
are the common terms for mental dysfunction in a cancer patient/survivor under the influence …