Pathophysiological response to trauma-induced coagulopathy: a comprehensive review
Hypercoagulability can occur after severe tissue injury, that is likely related to tissue factor
exposure and impaired endothelial release of tissue plasminogen activator (tPA). In contrast …
exposure and impaired endothelial release of tissue plasminogen activator (tPA). In contrast …
The European guideline on management of major bleeding and coagulopathy following trauma
DR Spahn, B Bouillon, V Cerny, J Duranteau… - Critical care, 2019 - Springer
Background Severe traumatic injury continues to present challenges to healthcare systems
around the world, and post-traumatic bleeding remains a leading cause of potentially …
around the world, and post-traumatic bleeding remains a leading cause of potentially …
Management of coagulopathy in bleeding patients
S Hofer, CJ Schlimp, S Casu, E Grouzi - Journal of Clinical Medicine, 2021 - mdpi.com
Early recognition of coagulopathy is necessary for its prompt correction and successful
management. Novel approaches, such as point-of-care testing (POC) and administration of …
management. Novel approaches, such as point-of-care testing (POC) and administration of …
Efficacy of prehospital administration of fibrinogen concentrate in trauma patients bleeding or presumed to bleed (FIinTIC): a multicentre, double-blind, placebo …
B Ziegler, M Bachler, H Haberfellner… - European Journal of …, 2021 - journals.lww.com
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Fibrinogen Early In Severe Trauma studY (FEISTY): study protocol for a randomised controlled trial
Background Haemorrhage is a leading cause of death in severe trauma. Fibrinogen plays a
critical role in maintaining haemostasis in traumatic haemorrhage. Early fibrinogen …
critical role in maintaining haemostasis in traumatic haemorrhage. Early fibrinogen …
[HTML][HTML] Fibrinogen Early In Severe Trauma studY (FEISTY): results from an Australian multicentre randomised controlled pilot trial
J Winearls, M Wullschleger, E Wake… - Critical Care and …, 2021 - Elsevier
Background: Haemorrhage is a major cause of death in severe trauma. Fibrinogen plays a
critical role in maintaining haemostasis in traumatic haemorrhage, and early replacement …
critical role in maintaining haemostasis in traumatic haemorrhage, and early replacement …
Hypovolemic and hemorrhagic shock
H Lier, M Bernhard, B Hossfeld - Der Anaesthesist, 2018 - Springer
Zusammenfassung Der Begriff „Schock “bezeichnet eine lebensbedrohliche
Kreislaufsituation durch ein Missverhältnis von Sauerstoffangebot und-bedarf auf zellulärer …
Kreislaufsituation durch ein Missverhältnis von Sauerstoffangebot und-bedarf auf zellulärer …
Use of fibrinogen concentrate for trauma-related bleeding: a systematic-review and meta-analysis
SN Stabler, SS Li, A Karpov, EN Vu - Journal of Trauma and Acute …, 2020 - journals.lww.com
BACKGROUND Trauma-induced coagulopathy contributes to significant morbidity and
mortality in patients who experience trauma-related bleeding. This study aimed to …
mortality in patients who experience trauma-related bleeding. This study aimed to …
Variations and obstacles in the use of coagulation factor concentrates for major trauma bleeding across Europe: outcomes from a European expert meeting
V Černý, M Maegele, V Agostini, D Fries… - European Journal of …, 2021 - Springer
Purpose Trauma is a leading cause of mortality, with major bleeding and trauma-induced
coagulopathy (TIC) contributing to negative patient outcomes. Treatments for TIC include …
coagulopathy (TIC) contributing to negative patient outcomes. Treatments for TIC include …
Use of factor concentrates for the management of perioperative bleeding: guidance from the SSC of the ISTH
Perioperative bleeding is a common complication following major surgery. Despite surgical
measures to minimize bleeding, patients develop acquired hemostatic defects as a result of …
measures to minimize bleeding, patients develop acquired hemostatic defects as a result of …