Evolving characterization of the human hyperdirect pathway
The hyperdirect pathway (HDP) represents the main glutamatergic input to the subthalamic
nucleus (STN), through which the motor and prefrontal cerebral cortex can modulate basal …
nucleus (STN), through which the motor and prefrontal cerebral cortex can modulate basal …
[HTML][HTML] The neuroanatomical and neurochemical basis of apathy and impulsivity in frontotemporal lobar degeneration
L Passamonti, CJ Lansdall, JB Rowe - Current opinion in behavioral …, 2018 - Elsevier
Highlights•Apathy and impulsivity are common consequences of frontotemporal lobar
degeneration syndromes.•Common frontostriatal loops mediate different modes of apathy …
degeneration syndromes.•Common frontostriatal loops mediate different modes of apathy …
Distinct mechanisms mediate speed-accuracy adjustments in cortico-subthalamic networks
Optimal decision-making requires balancing fast but error-prone and more accurate but
slower decisions through adjustments of decision thresholds. Here, we demonstrate two …
slower decisions through adjustments of decision thresholds. Here, we demonstrate two …
The drift diffusion model as the choice rule in inter-temporal and risky choice: A case study in medial orbitofrontal cortex lesion patients and controls
J Peters, M D'Esposito - PLoS computational biology, 2020 - journals.plos.org
Sequential sampling models such as the drift diffusion model (DDM) have a long tradition in
research on perceptual decision-making, but mounting evidence suggests that these models …
research on perceptual decision-making, but mounting evidence suggests that these models …
Agitation and impulsivity in mid and late life as possible risk markers for incident dementia
DR Bateman, S Gill, S Hu, ED Foster… - … Research & Clinical …, 2020 - Wiley Online Library
To identify knowledge gaps regarding new‐onset agitation and impulsivity prior to onset of
cognitive impairment or dementia the International Society to Advance Alzheimer's …
cognitive impairment or dementia the International Society to Advance Alzheimer's …
Medications, deep brain stimulation, and other factors influencing impulse control disorders in Parkinson's disease
RS Eisinger, A Ramirez-Zamora, S Carbunaru… - Frontiers in …, 2019 - frontiersin.org
Impulse control disorders (ICDs) in Parkinson's disease (PD) have a high cumulative
incidence and negatively impact quality of life. ICDs are influenced by a complex interaction …
incidence and negatively impact quality of life. ICDs are influenced by a complex interaction …
Inhibitory dysfunction contributes to some of the motor and non-motor symptoms of movement disorders and psychiatric disorders
M Jahanshahi, JC Rothwell - … Transactions of the …, 2017 - royalsocietypublishing.org
Recently, it has been proposed that similar to goal-directed and habitual action mediated by
the fronto-striatal circuits, the fronto-striato-subthalamic-pallidal-thalamo-cortical network …
the fronto-striatal circuits, the fronto-striato-subthalamic-pallidal-thalamo-cortical network …
[HTML][HTML] Slow and steady? Strategic adjustments in response caution are moderately reliable and correlate across tasks
Speed-accuracy trade-offs are often considered a confound in speeded choice tasks, but
individual differences in strategy have been linked to personality and brain structure. We ask …
individual differences in strategy have been linked to personality and brain structure. We ask …
[HTML][HTML] Low and variable correlation between reaction time costs and accuracy costs explained by accumulation models: Meta-analysis and simulations.
The underpinning assumption of much research on cognitive individual differences (or
group differences) is that task performance indexes cognitive ability in that domain. In many …
group differences) is that task performance indexes cognitive ability in that domain. In many …
Effects of deep brain stimulation frequency on eye movements and cognitive control
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an effective treatment for
Parkinson's disease (PD). Varying the frequency DBS has differential effects on axial and …
Parkinson's disease (PD). Varying the frequency DBS has differential effects on axial and …