Graph theory-based sequence descriptors as remote homology predictors

G Agüero-Chapin, D Galpert, R Molina-Ruiz… - Biomolecules, 2019 - mdpi.com
Alignment-free (AF) methodologies have increased in popularity in the last decades as
alternative tools to alignment-based (AB) algorithms for performing comparative sequence …

PTML Model for Proteome Mining of B-Cell Epitopes and Theoretical–Experimental Study of Bm86 Protein Sequences from Colima, Mexico

SG Martinez-Arzate, E Tenorio-Borroto… - Journal of proteome …, 2017 - ACS Publications
In this work, we developed a general perturbation theory and machine learning method for
data mining of proteomes to discover new B-cell epitopes useful for vaccine design. The …

PTML model of enzyme subclasses for mining the proteome of biofuel producing microorganisms

R Concu, MN DS Cordeiro, CR Munteanu… - Journal of proteome …, 2019 - ACS Publications
Predicting enzyme function and enzyme subclasses is always a key objective in fields such
as biotechnology, biochemistry, medicinal chemistry, physiology, and so on. The Protein …

State of the art review and report of new tool for drug discovery

Y Martinez-Lopez, Y Caballero… - Current topics in …, 2017 - ingentaconnect.com
Background: There are a great number of tools that can be used in QSAR/QSPR studies;
they are implemented in several programs that are reviewed in this report. The usefulness of …

Experimental–computational study of carbon nanotube effects on mitochondrial respiration: In silico nano-QSPR machine learning models based on new Raman …

M González-Durruthy, LC Alberici, C Curti… - Journal of Chemical …, 2017 - ACS Publications
The study of selective toxicity of carbon nanotubes (CNTs) on mitochondria (CNT-
mitotoxicity) is of major interest for future biomedical applications. In the current work, the …

RExPRT: a machine learning tool to predict pathogenicity of tandem repeat loci

S Fazal, MC Danzi, I Xu, SN Kobren, S Sunyaev… - Genome biology, 2024 - Springer
Expansions of tandem repeats (TRs) cause approximately 60 monogenic diseases. We
expect that the discovery of additional pathogenic repeat expansions will narrow the …

Alignment-free method to predict enzyme classes and subclasses

R Concu, MNDS Cordeiro - International journal of molecular sciences, 2019 - mdpi.com
The Enzyme Classification (EC) number is a numerical classification scheme for enzymes,
established using the chemical reactions they catalyze. This classification is based on the …

Carbon nanotubes' effect on mitochondrial oxygen flux dynamics: Polarography experimental study and machine learning models using star graph trace invariants of …

M González-Durruthy, JM Monserrat, B Rasulev… - Nanomaterials, 2017 - mdpi.com
This study presents the impact of carbon nanotubes (CNTs) on mitochondrial oxygen mass
flux (Jm) under three experimental conditions. New experimental results and a new …

[PDF][PDF] Degree-based multiplicative atom-bond connectivity index of nanostructures

W Gao, MK Jamil, W Nazeer… - IAENG International journal …, 2017 - researchgate.net
There are a lot of nanomaterials and related chemical substances synthesized in the
laboratory every year, which makes the test of their performance has become a hard work …

The first eNanoMapper prototype: A substance database to support safe-by-design

N Jeliazkova, P Doganis, B Fadeel… - 2014 IEEE …, 2014 - ieeexplore.ieee.org
The EU-funded eNanoMapper project proposes a computational infrastructure for
toxicological data management of engineered nanomaterials (ENMs) based on open …