Dysregulation of immunological and inflammatory processes is frequently observed in
psychotic disorders. Numerous studies have examined the complex components of innate …

There is extensive bi-directional communication between the brain and the immune system
in both health and disease. In recent years, the role of an altered immune system in the …

Schizophrenia, bipolar disorder and major depressive disorder (MDD) have all been
associated with aberrant blood cytokine levels; however, neither the pattern of cytokine …

It has been postulated that schizophrenia (SZ) is related to a lower expression of brain-
derived neurotrophic factor (BDNF). In the past few years, an increasing number of divergent …

Objectives Cognitive dysfunction has been identified as a major symptom of a series of
psychiatric disorders. Multidisciplinary studies have shown that cognitive dysfunction is …

Depressed patients show evidence of both proinflammatory changes and
neurophysiological abnormalities such as increased amygdala reactivity and volumetric …

BACKGROUND: Previous studies suggest elevated inflammation in schizophrenia and
bipolar disorder, with increased activity of the Interleukin 1 (IL-1), interleukin 6 (IL-6), tumor …

Since the discovery of chlorpromazine in the 1950's, antipsychotic drugs have been the
cornerstone of treatment of schizophrenia, and all attenuate dopamine transmission at the …

Objective The present study aimed to examine the changes in pro-inflammatory cytokines
and body weight during 6-month risperidone treatment in drug naïve, first-episode …

In many individuals with major neuropsychiatric disorders including depression, bipolar
disorder and schizophrenia, their disease characteristics are consistent with a …