Cancer development and progression are closely associated with changes both in the
mechano-cellular phenotype of cancer and stromal cells and in the extracellular matrix …

Cancer preventive activities of green tea and its main constituent,(−)-epigallocatechin
gallate (EGCG) have been extensively studied by scientists all over the world. Since 1983 …

The interplay between the mechanical properties of cells and the forces that they produce
internally or that are externally applied to them play an important role in maintaining the …

Mechanical properties of cells and extracellular matrix (ECM) play important roles in many
biological processes including stem cell differentiation, tumor formation, and wound healing …

Many tumors, such as types of sarcoma and breast cancer, stiffen as they grow in a host
healthy tissue, while individual cancer cells are becoming softer. Tumor stiffening poses …

Purpose To understand how nanomechanical stiffness affects metastatic potential, we
studied the relationship between cell migration, a characteristic of metastasis, and cell …

Cancer progression is closely related to changes in the structure and mechanical properties
of the tumor microenvironment (TME). In many solid tumors, including pancreatic cancer, the …

Malignant transformation, though primarily driven by genetic mutations in cells, is also
accompanied by specific changes in cellular and extra-cellular mechanical properties such …

The study of physical and mechanical features of cancer cells, or cancer cell
mechanobiology, is a new frontier in cancer research. Such studies may enhance our …

The exact molecular mechanisms of ovarian cancer platinum resistance are not well
understood, and biomarkers to reliably predict ovarian cancer resistance to platinum and …