Signaling pathways in obesity: mechanisms and therapeutic interventions
X Wen, B Zhang, B Wu, H Xiao, Z Li, R Li… - Signal transduction and …, 2022 - nature.com
Obesity is a complex, chronic disease and global public health challenge. Characterized by
excessive fat accumulation in the body, obesity sharply increases the risk of several …
excessive fat accumulation in the body, obesity sharply increases the risk of several …
Wnt signaling mediates TLR pathway and promote unrestrained adipogenesis and metaflammation: therapeutic targets for obesity and type 2 diabetes
Diabesity is the combination of type 2 diabetes and obesity characterized by chronic low-
grade inflammation. The Wnt signaling act as an evolutionary pathway playing crucial role in …
grade inflammation. The Wnt signaling act as an evolutionary pathway playing crucial role in …
A diet high in sugar-sweetened beverage and low in fruits and vegetables is associated with adiposity and a pro-inflammatory adipokine profile
Diet, obesity and adipokines play important roles in diabetes and CVD; yet, limited studies
have assessed the relationship between diet and multiple adipokines. This cross-sectional …
have assessed the relationship between diet and multiple adipokines. This cross-sectional …
Integration of transcriptomics and non-targeted metabolomics reveals the underlying mechanism of skeletal muscle development in duck during embryonic stage
Z Hu, X Liu - International Journal of Molecular Sciences, 2023 - mdpi.com
Skeletal muscle is an important economic trait in duck breeding; however, little is known
about the molecular mechanisms of its embryonic development. Here, the transcriptomes …
about the molecular mechanisms of its embryonic development. Here, the transcriptomes …
A unifying hypothesis for control of body weight and reproduction in seasonally breeding mammals
G Helfer, P Barrett, PJ Morgan - Journal of neuroendocrinology, 2019 - Wiley Online Library
Animals have evolved diverse seasonal variations in physiology and reproduction to
accommodate yearly changes in environmental and climatic conditions. These changes in …
accommodate yearly changes in environmental and climatic conditions. These changes in …
Activation of Wnt signaling in cortical neurons enhances glucose utilization through glycolysis
P Cisternas, P Salazar, C Silva-Álvarez… - Journal of Biological …, 2016 - ASBMB
The Wnt signaling pathway is critical for a number of functions in the central nervous system,
including regulation of the synaptic cleft structure and neuroprotection against injury …
including regulation of the synaptic cleft structure and neuroprotection against injury …
Thermodynamics in gliomas: interactions between the canonical WNT/beta-catenin pathway and PPAR gamma
A Vallée, Y Lecarpentier, R Guillevin… - Frontiers in …, 2017 - frontiersin.org
Gliomas cells are the site of numerous metabolic and thermodynamics abnormalities with an
increasing entropy rate which is characteristic of irreversible processes driven by changes in …
increasing entropy rate which is characteristic of irreversible processes driven by changes in …
The crosstalk of hedgehog, PI3K and Wnt pathways in diabetes
Hyperglycaemia causes pancreatic β-cells to release insulin that then attaches to a specific
expression of receptor isoform and reverses high glucose concentrations. It is well known …
expression of receptor isoform and reverses high glucose concentrations. It is well known …
Primary cilia as a signaling platform for control of energy metabolism
JH Choi, MS Kim - Diabetes & metabolism journal, 2018 - synapse.koreamed.org
Obesity has become a common healthcare problem worldwide. Cilia are tiny hair-like
organelles on the cell surface that are generated and anchored by the basal body. Non …
organelles on the cell surface that are generated and anchored by the basal body. Non …
Leptin and chronic kidney diseases
S Mao, L Fang, F Liu, S Jiang, L Wu… - Journal of Receptors …, 2018 - Taylor & Francis
Chronic kidney diseases (CKD), a common outcome of various kidney diseases, cause a
series of refractory complications, which lead to great economic burdens on patients. The …
series of refractory complications, which lead to great economic burdens on patients. The …