Antidiabetic potential of medicinal plants and their active components
B Salehi, A Ata, N V. Anil Kumar, F Sharopov… - Biomolecules, 2019 - mdpi.com
Diabetes mellitus is one of the major health problems in the world, the incidence and
associated mortality are increasing. Inadequate regulation of the blood sugar imposes …
associated mortality are increasing. Inadequate regulation of the blood sugar imposes …
Recent updates on development of protein-tyrosine phosphatase 1B inhibitors for treatment of diabetes, obesity and related disorders
S Singh, AS Grewal, R Grover, N Sharma, B Chopra… - Bioorganic …, 2022 - Elsevier
The aim of this review was to discuss an overview of type 2 diabetes; biology of PTP1B; role
of PTP1B in metabolic disorders; and recent updates in the development of PTP1B inhibitors …
of PTP1B in metabolic disorders; and recent updates in the development of PTP1B inhibitors …
Emerging strategies for the activity assay and inhibitor screening of alpha-glucosidase
The high incidence of diabetes mellitus has caused widespread concern around the world,
and has quickly become one of the most prevalent and costly chronic diseases. Alpha …
and has quickly become one of the most prevalent and costly chronic diseases. Alpha …
Advances for pharmacological activities of Polygonum cuspidatum - A review
J Ke, MT Li, S Xu, J Ma, MY Liu, Y Han - Pharmaceutical biology, 2023 - Taylor & Francis
Abstract Context Polygonum cuspidatum Sieb. et Zucc (Polygonaceae), the root of which is
included in the Chinese Pharmcopoeia under the name 'Huzhang', has a long history as a …
included in the Chinese Pharmcopoeia under the name 'Huzhang', has a long history as a …
Progress in the discovery of naturally occurring anti-diabetic drugs and in the identification of their molecular targets
JH He, LX Chen, H Li - Fitoterapia, 2019 - Elsevier
Diabetes mellitus (DM), a chronic metabolic disease, severely affects patients' life and
intensively increases risks of developing other diseases. It is estimated that 0.4 billion …
intensively increases risks of developing other diseases. It is estimated that 0.4 billion …
Potential antidiabetic phytochemicals in plant roots: A review of in vivo studies
H Ardalani, F Hejazi Amiri, A Hadipanah… - Journal of Diabetes & …, 2021 - Springer
Background Medicinal plants are used to treat various disorders, including diabetes,
globally in a range of formulations. While attention has mainly been on the aerial plant parts …
globally in a range of formulations. While attention has mainly been on the aerial plant parts …
Antioxidant and Antidiabetic Activity of Proanthocyanidins from Fagopyrum dibotrys
X Li, J Liu, Q Chang, Z Zhou, R Han, Z Liang - Molecules, 2021 - mdpi.com
Proanthocyanidins are natural glycosidase inhibitors with excellent antioxidant activity. This
study aims to search for a new source of proanthocyanidins for the prevention and treatment …
study aims to search for a new source of proanthocyanidins for the prevention and treatment …
α-Glucosidase immobilization on functionalized Fe3O4 magnetic nanoparticles for screening of enzyme inhibitors
G Cheng, J Xing, Z Pi, S Liu, Z Liu, F Song - Chinese Chemical Letters, 2019 - Elsevier
Magnetic nanoparticles (MNPs) are widely used for the immobilization of enzyme owing to
the unique properties such as good biocompatibility and rapid separation. Herein, we used …
the unique properties such as good biocompatibility and rapid separation. Herein, we used …
Antidiabetic xanthones with α-glucosidase inhibitory activities from an endophytic Penicillium canescens
Worldwide, 463 million people are affected by diabetes of which the majority is diagnosed
with Type 2 Diabetes (T2D). T2D can ultimately lead to retinopathy, nephropathy, nerve …
with Type 2 Diabetes (T2D). T2D can ultimately lead to retinopathy, nephropathy, nerve …
Quickly screening for potential α-glucosidase inhibitors from guava leaves tea by bioaffinity ultrafiltration coupled with HPLC-ESI-TOF/MS method
L Wang, Y Liu, Y Luo, K Huang… - Journal of agricultural and …, 2018 - ACS Publications
Guava leaves tea (GLT) has a potential antihyperglycemic effect. Nevertheless, it is unclear
which compound plays a key role in reducing blood sugar. In this study, GLT extract (IC50 …
which compound plays a key role in reducing blood sugar. In this study, GLT extract (IC50 …