Inflammation and inflammatory cytokine contribute to the initiation and development of ulcerative colitis and its associated cancer

D Yao, M Dong, C Dai, S Wu - Inflammatory bowel diseases, 2019 - academic.oup.com
Dysregulated inflammatory responses play a pivotal role in the initiation, development, and
progression of tumors, as demonstrated by the association between ulcerative colitis and the …

[HTML][HTML] Obesity-induced TNFα and IL-6 signaling: the missing link between obesity and inflammation—driven liver and colorectal cancers

L Kern, MJ Mittenbühler, AJ Vesting, AL Ostermann… - Cancers, 2019 - mdpi.com
Cancers | Free Full-Text | Obesity-Induced TNFα and IL-6 Signaling: The Missing Link between
Obesity and Inflammation—Driven Liver and Colorectal Cancers Next Article in Journal Effects …

Colorectal cancer in ulcerative colitis: mechanisms, surveillance and chemoprevention

W Li, T Zhao, D Wu, J Li, M Wang, Y Sun, S Hou - Current Oncology, 2022 - mdpi.com
Patients with ulcerative colitis (UC) are at a two-to three-fold increased risk of developing
colorectal cancer (CRC) than the general population based on population-based data. UC …

Chocolate,“food of the gods”: History, science, and human health

MT Montagna, G Diella, F Triggiano… - International journal of …, 2019 - mdpi.com
Chocolate is well known for its fine flavor, and its history began in ancient times, when the
Maya considered chocolate (a cocoa drink prepared with hot water) the “Food of the Gods” …

Polyphenols: immunomodulatory and therapeutic implication in colorectal cancer

AM Mileo, P Nisticò, S Miccadei - Frontiers in immunology, 2019 - frontiersin.org
Polyphenolic compounds, widely present in fruits, vegetables, and cereals, have potential
benefits for human health and are protective agents against the development of …

Role of interleukin-6-mediated inflammation in the pathogenesis of inflammatory bowel disease: focus on the available therapeutic approaches and gut microbiome

A Shahini, A Shahini - Journal of Cell Communication and Signaling, 2023 - Springer
Inflammatory bowel disease (IBD) is considered a chronic inflammatory and multifactorial
disease of the gastrointestinal tract. Crohn's disease (CD) and ulcerative colitis (UC) are two …

Bioactivity of polyphenols: preventive and adjuvant strategies toward reducing inflammatory bowel diseases—promises, perspectives, and pitfalls

A Kaulmann, T Bohn - Oxidative medicine and cellular …, 2016 - Wiley Online Library
Inflammatory bowel diseases (IBDs) are characterized by autoimmune and inflammation‐
related complications of the large intestine (ulcerative colitis) and additional parts of the …

Interplay between dietary polyphenols and oral and gut microbiota in the development of colorectal cancer

C Cueva, M Silva, I Pinillos, B Bartolomé… - Nutrients, 2020 - mdpi.com
Colorectal cancer (CRC) is the third most diagnosed type of cancer worldwide. Dietary
features play an important role in its development, and the involvement of human microbial …

Polyphenolic phytochemicals in cancer prevention and therapy: bioavailability versus bioefficacy

JM Estrela, S Mena, E Obrador… - Journal of medicinal …, 2017 - ACS Publications
Natural polyphenols are organic chemicals which contain phenol units in their structures.
They show antitumor properties. However, a key problem is their short half-life and low …

[HTML][HTML] Biological characteristics of IL-6 and related intestinal diseases

Y Guo, B Wang, T Wang, L Gao, Z Yang… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
The intestine serves as an important digestive and the largest immune organ in the body.
Interleukin-6 (IL-6), an important mediator of various pathways, participates in the …