Reactive oxygen species, toxicity, oxidative stress, and antioxidants: Chronic diseases and aging

K Jomova, R Raptova, SY Alomar, SH Alwasel… - Archives of …, 2023 - Springer
A physiological level of oxygen/nitrogen free radicals and non-radical reactive species
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …

Oxidative stress and antioxidants in neurodegenerative disorders

EO Olufunmilayo, MB Gerke-Duncan, RMD Holsinger - Antioxidants, 2023 - mdpi.com
Neurodegenerative disorders constitute a substantial proportion of neurological diseases
with significant public health importance. The pathophysiology of neurodegenerative …

Curcumin: biological, pharmaceutical, nutraceutical, and analytical aspects

RR Kotha, DL Luthria - Molecules, 2019 - mdpi.com
Turmeric is a curry spice that originated from India, which has attracted great interest in
recent decades because it contains bioactive curcuminoids (curcumin, demethoxycurcumin …

Development of multifunctional molecules as potential therapeutic candidates for Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis in the …

MG Savelieff, G Nam, J Kang, HJ Lee, M Lee… - Chemical …, 2018 - ACS Publications
Neurodegenerative diseases pose a substantial socioeconomic burden on society.
Unfortunately, the aging world population and lack of effective cures foreshadow a negative …

Neuroprotective herbs for the management of Alzheimer's disease

J Gregory, YV Vengalasetti, DE Bredesen, RV Rao - Biomolecules, 2021 - mdpi.com
Background—Alzheimer's disease (AD) is a multifactorial, progressive, neurodegenerative
disease that is characterized by memory loss, personality changes, and a decline in …

Curcumin-loaded nanoparticles: A novel therapeutic strategy in treatment of central nervous system disorders

H Yavarpour-Bali, M Ghasemi-Kasman… - International journal of …, 2019 - Taylor & Francis
Curcumin as a hydrophobic polyphenol is extracted from the rhizome of Curcuma longa.
Curcumin is widely used as a dietary spice and a topical medication for the treatment of …

The chemistry of curcumin: from extraction to therapeutic agent

KI Priyadarsini - Molecules, 2014 - mdpi.com
Curcumin, a pigment from turmeric, is one of the very few promising natural products that
has been extensively investigated by researchers from both the biological and chemical …

Protective effects of Indian spice curcumin against amyloid-β in Alzheimer's disease

PH Reddy, M Manczak, X Yin… - Journal of …, 2018 - content.iospress.com
The purpose of our article is to assess the current understanding of Indian spice, curcumin,
against amyloid-ß (Aß)-induced toxicity in Alzheimer's disease (AD) pathogenesis. Natural …

Antioxidants in Alzheimer's disease: Current therapeutic significance and future prospects

P Pritam, R Deka, A Bhardwaj, R Srivastava, D Kumar… - Biology, 2022 - mdpi.com
Simple Summary Alzheimer's disease (AD) is the most common neurodegenerative disease,
intensifying impairments in cognition, behavior, and memory. Histopathological AD …

The beneficial role of curcumin on inflammation, diabetes and neurodegenerative disease: A recent update

S Ghosh, S Banerjee, PC Sil - Food and Chemical Toxicology, 2015 - Elsevier
The concept of using phytochemicals has ushered in a new revolution in pharmaceuticals.
Naturally occurring polyphenols (like curcumin, morin, resveratrol, etc.) have gained …