This article focuses on the description of some of the NMR techniques used in the field of
biomedical and pharmaceutical research. Indeed, the NMR method has special …

Minor variation in the composition of a mixture can have acute effects on its characteristic
properties, such as flavour, efficacy or toxicity. Thus, the analysis of complex mixtures is of …

This work aims at characterizing the metabolic profile of human lung cancer, to gain new
insights into tumor metabolism and to identify possible biomarkers with potential diagnostic …

This article reviews the methodological aspects of detecting low-abundant J-coupled
metabolites via 1D spectral editing techniques and 2D nuclear magnetic resonance (NMR) …

Purpose To use localized correlated spectroscopy (COSY) to assess for an altered
biochemical state or states in breast tissue of women with BRCA gene mutations that …

Background Much research has been devoted to the development of new breast cancer
diagnostic measures, including those involving high-resolution magic angle spinning (HR …

Objectives Despite improved survival due to new treatments, the 10-year survival rate in
patients with breast cancer is approximately 75%. Lymphovascular invasion (LVI), a …

Objective The adjacent vessel sign (AVS) is a descriptor for differentiating malignant from
benign breast lesions on breast MRI (bMRI). This investigation was designed to verify the …

MRI and in vivo MRS have rapidly evolved as sensitive tools for diagnosis and therapeutic
monitoring in cancer research. In vivo MRS provides information on tumor metabolism …

Objectives: The main objective of this work was to detect novel biomarkers in breast cancer
by spreading the MR spectra over two dimensions in multiple spatial locations using an …