Tackling drug resistance and other causes of treatment failure in leishmaniasis

GJ Wijnant, F Dumetz, L Dirkx, D Bulté… - Frontiers in Tropical …, 2022 - frontiersin.org
Leishmaniasis is a tropical infectious disease caused by the protozoan Leishmania parasite.
The disease is transmitted by female sand flies and, depending on the infecting parasite …

[HTML][HTML] Visceral leishmaniasis: a global overview

RG Wamai, J Kahn, J McGloin, G Ziaggi - Journal of Global Health …, 2020 - e-jghs.org
The leishmaniases are protozoan infections that are among the neglected tropical diseases
(NTDs). Over one billion people are at risk of these diseases in virtually all continents. These …

Sex‐Related Differences in Immune Response and Symptomatic Manifestations to Infection with Leishmania Species

RD Lockard, ME Wilson… - Journal of immunology …, 2019 - Wiley Online Library
Worldwide, an estimated 12 million people are infected with Leishmania spp. and an
additional 350 million are at risk of infection. Leishmania are intracellular parasites that …

Human leishmaniasis vaccines: Use cases, target population and potential global demand

S Malvolti, M Malhame, CF Mantel… - PLoS Neglected …, 2021 - journals.plos.org
The development of vaccines against one or all forms of human leishmaniasis remains
hampered by a paucity of investment, at least in part resulting from the lack of well …

Prevalence of human visceral leishmaniasis in Iran: A systematic review and meta-analysis

M Rostamian, H Bashiri, V Yousefinejad… - … and infectious diseases, 2021 - Elsevier
Leishmania infantum is the main cause of human visceral leishmaniasis (HVL; also known
as kala-azar) in the Middle East and may be fatal if left untreated. This disease was first …

Modelling the impact of COVID-19-related programme interruptions on visceral leishmaniasis in India

EA Le Rutte, LE Coffeng, J Muñoz… - Transactions of The …, 2021 - academic.oup.com
Abstract Background In March 2020, India declared a nationwide lockdown to control the
spread of coronavirus disease 2019. As a result, control efforts against visceral …

Policy recommendations from transmission modeling for the elimination of visceral leishmaniasis in the Indian subcontinent

EA Le Rutte, LAC Chapman, LE Coffeng… - Clinical Infectious …, 2018 - academic.oup.com
Background Visceral leishmaniasis (VL) has been targeted by the World Health
Organization (WHO) and 5 countries in the Indian subcontinent for elimination as a public …

Gene-specific sex effects on susceptibility to infectious diseases

M Lipoldová, P Demant - Frontiers in immunology, 2021 - frontiersin.org
Inflammation is an integral part of defense against most infectious diseases. These
pathogen-induced immune responses are in very many instances strongly influenced by …

Age trends in asymptomatic and symptomatic Leishmania donovani infection in the Indian subcontinent: A review and analysis of data from diagnostic and …

LAC Chapman, ALK Morgan, ER Adams… - PLoS neglected …, 2018 - journals.plos.org
Background Age patterns in asymptomatic and symptomatic infection with Leishmania
donovani, the causative agent of visceral leishmaniasis (VL) in the Indian subcontinent …

Active surveillance identified a neglected burden of macular cases of Post Kala-azar Dermal Leishmaniasis in West Bengal

R Sengupta, SJ Chaudhuri, S Moulik… - PLoS neglected …, 2019 - journals.plos.org
Background Post Kala-azar Dermal Leishmaniasis (PKDL) develops in patients apparently
cured of Visceral Leishmaniasis (VL), and is the strongest contender for being the disease …