The ability to culture cells in vitro has revolutionized hypothesis testing in basic cell and
molecular biology research and has become a standard methodology in drug screening and …

Microfabricated systems provide an excellent platform for the culture of cells, and are an
extremely useful tool for the investigation of cellular responses to various stimuli …

Neuronal networks underlie memory storage and information processing in the human
brain, and ultimately participate in what Eccles referred to as “the creation of …

In vitro culture of small neuronal networks with pre-defined topological features is
particularly desirable when the electrical activity of such assemblies can be monitored for …

The field of neuroscience has always been attractive to engineers. Neurons and their
connections, like tiny circuit elements, process and transmit information in a dramatic way …

We describe a novel and noninvasive, microscopy-based method for visualizing the
structure and dynamics of microbial biofilms, individual fluorescent microbial cells, and …

Understanding the mechanisms that govern nervous tissues function remains a challenge.
In vitro two-dimensional (2D) cell culture systems provide a simplistic platform to evaluate …

We describe how the amorphous fluoropolymer CYTOP can be advantageously used as a
waveguide cladding material in integrated optical circuits suitable for applications in …

We present a detailed account of processing issues related to fabrication of optical
waveguide sensors intended for evanescent-wave sensing in aqueous solutions or surface …

In this work, two different micro-patterning methods for use in the growth guidance of
dissociated primary culture neuron cells are compared: open chemically patterned growth …