The tumour microenvironment (TME) highly influences the growth and spread of tumours,
thus impacting the patient's clinical outcome. In this context, the complement system plays a …

The complement system, an essential part of the innate immune system, is composed of a
group of secreted and membrane proteins that collectively participate in maintaining the …

Endometriosis (EM) is a chronic disease characterized by the presence and proliferation of
functional endometrial glands and stroma outside the uterine cavity. Ovaries and pelvic …

Biomarkers are detectable molecules that can reflect specific physiological states of cells,
organs, and organisms and therefore be regarded as indicators for specific diseases. And …

The tumor microenvironment (TME) has important effects on the tumorigenesis and
development of osteosarcoma (OS). However, the dynamic mechanism regulating TME …

C1q is the recognition molecule of the classical pathway of the complement system. By
binding to its targets, such as antigen-bound immunoglobulins or C-reactive protein, C1q …

The complement system represents one of the evolutionary oldest arms of our immune
system and is commonly recognized as a liver‐derived and serum‐active system critical for …

The contribution of the complement system in the pathophysiology of brain cancers has
been recently considered in light of its well-known involvement in carcinogenesis …

Background: Skin cutaneous melanoma (SKCM) is a common malignancy that is associated
with increased morbidity and mortality. Complement C1Q is composed of C1QA, C1QB, and …

Cancer-related inflammation plays a central role in the establishment of tumor-promoting
mechanisms. Tumor-associated myeloid cells, which engage in complex interactions with …