Comparative efficacy and safety of first-line antiretroviral therapy for the treatment of HIV infection: a systematic review and network meta-analysis
Background New antiretroviral therapy (ART) regimens for HIV could improve clinical
outcomes for patients. To inform global guidelines, we aimed to assess the comparative …
outcomes for patients. To inform global guidelines, we aimed to assess the comparative …
Efavirenz in the therapy of HIV infection
NY Rakhmanina, JN Van den Anker - Expert opinion on drug …, 2010 - Taylor & Francis
Importance of the field: The use of the first generation non-nucleoside reverse transcriptase
inhibitor efavirenz (EFV) as a component of first-line antiretroviral therapy has been …
inhibitor efavirenz (EFV) as a component of first-line antiretroviral therapy has been …
Risk of myocardial infarction in patients with HIV infection exposed to specific individual antiretroviral drugs from the 3 major drug classes: the data collection on …
SW Worm, C Sabin, R Weber, P Reiss… - The Journal of …, 2010 - academic.oup.com
Background. The risk of myocardial infarction (MI) in patients with human immunodeficiency
virus (HIV) infection has been assessed in 13 anti-HIV drugs in the Data Collection on …
virus (HIV) infection has been assessed in 13 anti-HIV drugs in the Data Collection on …
Class of antiretroviral drugs and the risk of myocardial infarction
DAD Study Group - New England Journal of Medicine, 2007 - Mass Medical Soc
Background We have previously demonstrated an association between combination
antiretroviral therapy and the risk of myocardial infarction. It is not clear whether this …
antiretroviral therapy and the risk of myocardial infarction. It is not clear whether this …
Treatment for adult HIV infection: 2006 recommendations of the International AIDS Society–USA panel
SM Hammer, MS Saag, M Schechter, JSG Montaner… - Jama, 2006 - jamanetwork.com
ContextGuidelines for antiretroviral therapy are important for clinicians worldwide given the
complexity of the field and the varied clinical situations in which these agents are used. The …
complexity of the field and the varied clinical situations in which these agents are used. The …
Impact of individual antiretroviral drugs on the risk of myocardial infarction in human immunodeficiency virus–infected patients: a case-control study nested within the …
S Lang, M Mary-Krause, L Cotte, J Gilquin… - Archives of internal …, 2010 - jamanetwork.com
Background The role of exposure to specific antiretroviral drugs on risk of myocardial
infarction in human immunodeficiency virus (HIV)–infected patients is debated in the …
infarction in human immunodeficiency virus (HIV)–infected patients is debated in the …
[HTML][HTML] HIV and HAART-associated dyslipidemia
ER Feeney, PWG Mallon - The open cardiovascular medicine …, 2011 - ncbi.nlm.nih.gov
Effective highly active antiretroviral therapy (HAART) for human immunodeficiency virus-1
(HIV) infection has led to marked improvement in life-expectancy for those infected with HIV …
(HIV) infection has led to marked improvement in life-expectancy for those infected with HIV …
Greater decrease in bone mineral density with protease inhibitor regimens compared with nonnucleoside reverse transcriptase inhibitor regimens in HIV-1 infected …
C Duvivier, S Kolta, L Assoumou, J Ghosn… - Aids, 2009 - journals.lww.com
Objective: To evaluate the change in bone mineral density (BMD) at specific sites in patients
initiating antiretroviral therapy in a substudy of the ANRS 121 trial. Methods: Antiretroviral …
initiating antiretroviral therapy in a substudy of the ANRS 121 trial. Methods: Antiretroviral …
Interruption of antiretroviral therapy and risk of cardiovascular disease in persons with HIV-1 infection: exploratory analyses from the SMART trial
AN Phillips, A Carr, J Neuhaus… - Antiviral …, 2008 - journals.sagepub.com
Background The SMART trial found a raised risk of cardiovascular disease (CVD) events in
patients undergoing CD4+ T cell-count guided intermittent antiretroviral therapy (ART) …
patients undergoing CD4+ T cell-count guided intermittent antiretroviral therapy (ART) …
Non-nucleoside reverse transcriptase inhibitor efavirenz activates PXR to induce hypercholesterolemia and hepatic steatosis
Background & Aims The most prescribed non-nucleoside reverse transcriptase inhibitor,
efavirenz, has been associated with elevated risk of dyslipidemia and hepatic steatosis in …
efavirenz, has been associated with elevated risk of dyslipidemia and hepatic steatosis in …