Forkhead box proteins: tuning forks for transcriptional harmony

EWF Lam, JJ Brosens, AR Gomes, CY Koo - Nature Reviews Cancer, 2013 - nature.com
Forkhead box (FOX) proteins are multifaceted transcription factors that are responsible for
fine-tuning the spatial and temporal expression of a broad range of genes both during …

FOXM1: From cancer initiation to progression and treatment

CY Koo, KW Muir, EWF Lam - Biochimica et Biophysica Acta (BBA)-Gene …, 2012 - Elsevier
The Forkhead box protein M1 (FOXM1) transcription factor is a regulator of myriad biological
processes, including cell proliferation, cell cycle progression, cell differentiation, DNA …

[HTML][HTML] Ethyl carbamate triggers ferroptosis in liver through inhibiting GSH synthesis and suppressing Nrf2 activation

Y Xu, Y Li, J Li, W Chen - Redox biology, 2022 - Elsevier
Humans are inevitably exposed to ethyl carbamate (EC) via consumption of fermented food
and beverages. EC, known as an environmental toxin, can cause oxidative stress-mediated …

A Positive Feedback Loop of lncRNA-PVT1 and FOXM1 Facilitates Gastric Cancer Growth and Invasion

M Xu, Y Wang, W Weng, P Wei, P Qi, Q Zhang… - Clinical Cancer …, 2017 - AACR
Purpose: The long, noncoding RNA (lncRNA) PVT1 is an important epigenetic regulator with
a critical role in human tumors. Here, we aimed to investigate the clinical application and the …

FOXM1: A small fox that makes more tracks for cancer progression and metastasis

MA Khan, P Khan, A Ahmad, M Fatima… - Seminars in Cancer …, 2023 - Elsevier
Transcription factors (TFs) are indispensable for the modulation of various signaling
pathways associated with normal cell homeostasis and disease conditions. Among cancer …

FOX (M1) news—it is cancer

M Halasi, AL Gartel - Molecular cancer therapeutics, 2013 - AACR
FOXM1 is an oncogenic transcription factor of the Forkhead family and it has a well-defined
role in cell proliferation and cell-cycle progression. Expression of FOXM1 is excluded in …

FoxM1 and Wnt/β-catenin signaling in glioma stem cells

A Gong, S Huang - Cancer research, 2012 - AACR
Cancer stem cells may be responsible for tumor initiation and maintenance. The molecular
mechanisms that control cancer stem cells are related to alterations in various signaling …

Multiple faces of FoxM1 transcription factor: lessons from transgenic mouse models

TV Kalin, V Ustiyan, VV Kalinichenko - Cell cycle, 2011 - Taylor & Francis
FoxM1 transcription factor (previously called HFH-11B, Trident, FoxM1b, Win, and MPP2) is
expressed in actively dividing cells and critical for cell cycle progression. FoxM1 expression …

Ultra-high dose-rate proton FLASH improves tumor control

S Shukla, T Saha, N Rama, A Acharya, T Le… - Radiotherapy and …, 2023 - Elsevier
Background and purpose Proton radiotherapy (PRT) offers potential benefits over other
radiation modalities, including photon and electron radiotherapy. Increasing the rate at …

The transcription factor FOXM1 (Forkhead box M1): proliferation-specific expression, transcription factor function, target genes, mouse models, and normal biological …

I Wierstra - Advances in cancer research, 2013 - Elsevier
Abstract FOXM1 (Forkhead box M1) is a typical proliferation-associated transcription factor,
which stimulates cell proliferation and exhibits a proliferation-specific expression pattern …