It is widely held that schizophrenia involves an active process of peripheral inflammation that
induces or reflects brain inflammation with activation of microglia, the brain's resident …

The discovery of FOXP3+ regulatory T (Treg) cells as a distinct cell lineage with a central
role in regulating immune responses provided a deeper understanding of self-tolerance …

Regulatory T (Treg) cells are critical for maintaining immune homeostasis and preventing
autoimmunity. Here, we show that the non-oxidative pentose phosphate pathway (PPP) …

The functional integrity of Tregs is interwoven with cellular metabolism; however, the
mechanisms governing Treg metabolic programs remain elusive. Here, we identified that the …

The discovery of the transcription factor Forkhead box-p3 (Foxp3) has shed fundamental
insights into the understanding of the molecular determinants leading to generation and …

FOXP1 is ubiquitously expressed in the human body and is implicated in both physiological
and pathological processes including cancer. However, despite its importance the role of …

FOXP1 syndrome is a neurodevelopmental disorder caused by mutations or deletions that
disrupt the forkhead box protein 1 (FOXP1) gene, which encodes a transcription factor …

Regulatory T cells (Tregs) are instrumental in maintaining immune tolerance and preventing
destructive autoimmunity, but how heterogeneous Treg populations are established remains …

Introduction Plant-based nutritional programming is the concept of exposing fish at very
early life stages to a plant-based diet for a short duration to improve physiological responses …

Background Cardiovascular disease had a global prevalence of 523 million cases and 18.6
million deaths in 2019. The current standard for diagnosing coronary artery disease (CAD) is …