Understanding the extracellular vesicle surface for clinical molecular biology
Extracellular vesicles (EVs) are lipid‐membrane enclosed nanoparticles that play significant
roles in health and disease. EVs are abundant in body fluids and carry an array of molecules …
roles in health and disease. EVs are abundant in body fluids and carry an array of molecules …
[HTML][HTML] Nanomaterials for diagnosis and treatment of brain cancer: Recent updates
Brain tumors, especially glioblastoma, remain the most aggressive form of all the cancers
because of inefficient diagnosis and profiling. Nanostructures, such as metallic …
because of inefficient diagnosis and profiling. Nanostructures, such as metallic …
[HTML][HTML] Circulating biomarkers in patients with glioblastoma
J Müller Bark, A Kulasinghe, B Chua, BW Day… - British journal of …, 2020 - nature.com
Gliomas are the most common tumours of the central nervous system and the most
aggressive form is glioblastoma (GBM). Despite advances in treatment, patient survival …
aggressive form is glioblastoma (GBM). Despite advances in treatment, patient survival …
[HTML][HTML] Cell-derived extracellular vesicles can be used as a biomarker reservoir for glioblastoma tumor subtyping
R Lane, T Simon, M Vintu, B Solkin, B Koch… - Communications …, 2019 - nature.com
Glioblastoma (GBM) is one of the most aggressive solid tumors for which treatment options
and biomarkers are limited. Small extracellular vesicles (sEVs) produced by both GBM and …
and biomarkers are limited. Small extracellular vesicles (sEVs) produced by both GBM and …
Advances in nanomedicines for diagnosis of central nervous system disorders
In spite of a great improvement in medical health services and an increase in lifespan, we
have witnessed a skyrocket increase in the incidence of central nervous system (CNS) …
have witnessed a skyrocket increase in the incidence of central nervous system (CNS) …
[HTML][HTML] The role of extracellular vesicles in the physiological and pathological regulation of the blood–brain barrier
Extracellular vesicles (EVs) are a subclass of biological nanoparticles secreted by most cell
types. Once secreted, EVs can travel long distances to deliver their content to target cells …
types. Once secreted, EVs can travel long distances to deliver their content to target cells …
Circulating biomarkers for glioma: a review
J Jones, H Nguyen, K Drummond, A Morokoff - Neurosurgery, 2021 - journals.lww.com
Accurate circulating biomarkers have potential clinical applications in population screening,
tumor subclassification, monitoring tumor status, and the delivery of individualized …
tumor subclassification, monitoring tumor status, and the delivery of individualized …
Extracellular vesicles: The key for precision medicine in glioblastoma
Glioblastoma (GBM) represents the most aggressive and lethal disease of the central
nervous system. Diagnosis is delayed following the occurrence of symptoms, and treatment …
nervous system. Diagnosis is delayed following the occurrence of symptoms, and treatment …
Pseudoprogression versus true progression in glioblastoma patients: A multiapproach literature review. Part 2–Radiological features and metric markers
C Le Fevre, JM Constans, I Chambrelant… - Critical reviews in …, 2021 - Elsevier
After chemoradiotherapy for glioblastoma, pseudoprogression can occur and must be
distinguished from true progression to correctly manage glioblastoma treatment and follow …
distinguished from true progression to correctly manage glioblastoma treatment and follow …
[HTML][HTML] Glioblastoma biomarkers in urinary extracellular vesicles reveal the potential for a 'liquid gold'biopsy
Background Biomarkers that reflect glioblastoma tumour activity and treatment response are
urgently needed to help guide clinical management, particularly for recurrent disease. As the …
urgently needed to help guide clinical management, particularly for recurrent disease. As the …