Understanding the extracellular vesicle surface for clinical molecular biology

S Hallal, Á Tűzesi, GE Grau… - Journal of …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) are lipid‐membrane enclosed nanoparticles that play significant
roles in health and disease. EVs are abundant in body fluids and carry an array of molecules …

[HTML][HTML] Nanomaterials for diagnosis and treatment of brain cancer: Recent updates

M Mukhtar, M Bilal, A Rahdar, M Barani, R Arshad… - Chemosensors, 2020 - mdpi.com
Brain tumors, especially glioblastoma, remain the most aggressive form of all the cancers
because of inefficient diagnosis and profiling. Nanostructures, such as metallic …

[HTML][HTML] Circulating biomarkers in patients with glioblastoma

J Müller Bark, A Kulasinghe, B Chua, BW Day… - British journal of …, 2020 - nature.com
Gliomas are the most common tumours of the central nervous system and the most
aggressive form is glioblastoma (GBM). Despite advances in treatment, patient survival …

[HTML][HTML] Cell-derived extracellular vesicles can be used as a biomarker reservoir for glioblastoma tumor subtyping

R Lane, T Simon, M Vintu, B Solkin, B Koch… - Communications …, 2019 - nature.com
Glioblastoma (GBM) is one of the most aggressive solid tumors for which treatment options
and biomarkers are limited. Small extracellular vesicles (sEVs) produced by both GBM and …

Advances in nanomedicines for diagnosis of central nervous system disorders

X Zhang, J Zhou, Z Gu, H Zhang, Q Gong, K Luo - Biomaterials, 2021 - Elsevier
In spite of a great improvement in medical health services and an increase in lifespan, we
have witnessed a skyrocket increase in the incidence of central nervous system (CNS) …

[HTML][HTML] The role of extracellular vesicles in the physiological and pathological regulation of the blood–brain barrier

S Busatto, G Morad, P Guo, MA Moses - FASEB BioAdvances, 2021 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) are a subclass of biological nanoparticles secreted by most cell
types. Once secreted, EVs can travel long distances to deliver their content to target cells …

Circulating biomarkers for glioma: a review

J Jones, H Nguyen, K Drummond, A Morokoff - Neurosurgery, 2021 - journals.lww.com
Accurate circulating biomarkers have potential clinical applications in population screening,
tumor subclassification, monitoring tumor status, and the delivery of individualized …

Extracellular vesicles: The key for precision medicine in glioblastoma

M Del Bene, D Osti, S Faletti, GV Beznoussenko… - Neuro …, 2022 - academic.oup.com
Glioblastoma (GBM) represents the most aggressive and lethal disease of the central
nervous system. Diagnosis is delayed following the occurrence of symptoms, and treatment …

Pseudoprogression versus true progression in glioblastoma patients: A multiapproach literature review. Part 2–Radiological features and metric markers

C Le Fevre, JM Constans, I Chambrelant… - Critical reviews in …, 2021 - Elsevier
After chemoradiotherapy for glioblastoma, pseudoprogression can occur and must be
distinguished from true progression to correctly manage glioblastoma treatment and follow …

[HTML][HTML] Glioblastoma biomarkers in urinary extracellular vesicles reveal the potential for a 'liquid gold'biopsy

SM Hallal, Á Tűzesi, LA Sida, E Xian, D Madani… - British Journal of …, 2024 - nature.com
Background Biomarkers that reflect glioblastoma tumour activity and treatment response are
urgently needed to help guide clinical management, particularly for recurrent disease. As the …