Neurogenesis following stroke affecting the adult brain

O Lindvall, Z Kokaia - Cold Spring Harbor perspectives …, 2015 - cshperspectives.cshlp.org
A bulk of experimental evidence supports the idea that the stroke-damaged adult brain
makes an attempt to repair itself by producing new neurons also in areas where …

Role of low‐level laser therapy in neurorehabilitation

JT Hashmi, YY Huang, BZ Osmani, SK Sharma… - Pm&r, 2010 - Wiley Online Library
This year marks the 50th anniversary of the discovery of the laser. The development of
lasers for medical use, which became known as low‐level laser therapy (LLLT) or …

Systemic administration of exosomes released from mesenchymal stromal cells promote functional recovery and neurovascular plasticity after stroke in rats

H Xin, Y Li, Y Cui, JJ Yang… - Journal of Cerebral …, 2013 - journals.sagepub.com
Here, for the first time, we test a novel hypothesis that systemic treatment of stroke with
exosomes derived from multipotent mesenchymal stromal cells (MSCs) promote …

[HTML][HTML] VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain

ZG Zhang, L Zhang, Q Jiang, R Zhang… - The Journal of …, 2000 - Am Soc Clin Investig
VEGF is a secreted mitogen associated with angiogenesis and is also a potent vascular
permeability factor. The biological role of VEGF in the ischemic brain remains unknown. This …

Treatment of stroke with erythropoietin enhances neurogenesis and angiogenesis and improves neurological function in rats

L Wang, Z Zhang, Y Wang, R Zhang, M Chopp - Stroke, 2004 - Am Heart Assoc
Background and Purpose—Erythropoietin (EPO) promotes proliferation and differentiation of
erythroid progenitors and the survival of maturing erythroid cells. Here, we investigated the …

Therapeutic benefit of intracerebral transplantation of bone marrow stromal cells after cerebral ischemia in rats

J Chen, Y Li, L Wang, M Lu, X Zhang… - Journal of the neurological …, 2001 - Elsevier
We tested the hypothesis that bone marrow stromal cells (MSCs) transplanted into the
ischemic boundary zone, survive, differentiate and improve functional recovery after middle …

Proliferation and differentiation of progenitor cells in the cortex and the subventricular zone in the adult rat after focal cerebral ischemia

RL Zhang, ZG Zhang, L Zhang, M Chopp - Neuroscience, 2001 - Elsevier
Progenitor cells in the subventricular zone of the lateral ventricle and in the dentate gyrus of
the hippocampus can proliferate throughout the life of the animal. To examine the …

Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke

J Chen, ZG Zhang, Y Li, Y Wang, L Wang… - Annals of …, 2003 - Wiley Online Library
We demonstrate that the 3‐hydroxy‐3‐methyl‐glutaryl‐coenzyme A (HMG‐CoA) reductase
inhibitors atorvastatin and simvastatin enhance functional outcome and induce brain …

Correlation of VEGF and angiopoietin expression with disruption of blood–brain barrier and angiogenesis after focal cerebral ischemia

ZG Zhang, L Zhang, W Tsang… - Journal of Cerebral …, 2002 - journals.sagepub.com
In an effort to elucidate the molecular mechanisms underlying cerebral vascular alteration
after stroke, the authors measured the spatial and temporal profiles of blood–brain barrier …

Activated neural stem cells contribute to stroke-induced neurogenesis and neuroblast migration toward the infarct boundary in adult rats

R Zhang, Z Zhang, L Wang, Y Wang… - Journal of Cerebral …, 2004 - journals.sagepub.com
Stroke increases neurogenesis. The authors investigated whether neural stem cells or
progenitor cells in the adult subventricular zone (SVZ) of rats contribute to stroke-induced …