Humoral immune responses at mucosal surfaces have historically focused on IgA. Growing
evidence highlights the complexity of IgA-inducing pathways and the functional impact of IgA …

Since the first description in 1989 of CD4‐Fc‐fusion antagonists that inhibit human immune
deficiency virus entry into T cells, Fc‐fusion proteins have been intensely investigated for …

Plasmodium falciparum malaria is a major cause of mortality and severe morbidity. Its
virulence is related to the parasite's ability to evade host immunity through clonal antigenic …

Plasmodium falciparum causes the most severe malaria in humans. Immunoglobulin M
(IgM) serves as the first line of humoral defense against infection and potently activates the …

Sequence diversity in pathogen antigens is an obstacle to the development of interventions
against many infectious diseases. In malaria caused by Plasmodium falciparum, the PfEMP1 …

FcR specific for pentameric IgM (FCMR) is expressed at high levels by B cells. Although
circulating IgM has profound effects on responses to pathogens, autoimmunity, and B cell …

Acquired protection from P lasmodium falciparum malaria takes years to develop, probably
reflecting the ability of the parasites to evade immunity. A recent example of this is the …

The formation of a histo (blood) group) ABO phenotype and the exclusion of an autoreactive
IgM or isoagglutinin activity arise apparently in identical glycosylation of complementary …

Plasmodium falciparum virulence is associated with sequestration of infected erythrocytes.
Microvascular binding mediated by PfEMP1 in complex with non-immune immunoglobulin M …

Abstract Background. People of the Fulani ethnic group are more resistant to malaria
compared with genetically distinct ethnic groups, such as the Dogon people, in West Africa …