Mechanisms of chemotherapy resistance in triple-negative breast cancer—how we can rise to the challenge

M Nedeljković, A Damjanović - Cells, 2019 - mdpi.com
Triple-negative (TNBC) is the most lethal subtype of breast cancer owing to high
heterogeneity, aggressive nature, and lack of treatment options. Chemotherapy remains the …

The multi-factorial nature of clinical multidrug resistance in cancer

YG Assaraf, A Brozovic, AC Gonçalves… - Drug resistance …, 2019 - Elsevier
Curative cancer therapy remains a major challenge particularly in cancers displaying
multidrug resistance (MDR). The MDR phenotype is characterized by cross-resistance to a …

MiRNA and LncRNA as potential biomarkers in triple-negative breast cancer: a review

SR Volovat, C Volovat, I Hordila, DA Hordila… - Frontiers in …, 2020 - frontiersin.org
Noncoding RNAs (ncRNAs) include a diverse range of RNA species, including microRNAs
(miRNAs) and long noncoding RNAs (lncRNAs). MiRNAs, ncRNAs of approximately 19–25 …

Recent treatment progress of triple negative breast cancer

Y Chang-Qing, L Jie, Z Shi-Qi, Z Kun, G Zi-Qian… - Progress in biophysics …, 2020 - Elsevier
Breast cancer (BC) is a serious worldwide disease that threatens women's health.
Particularly, the morbidity of triple-negative breast cancer (TNBC) is higher than that of other …

Molecular mechanisms, biomarkers and emerging therapies for chemotherapy resistant TNBC

P Ferrari, C Scatena, M Ghilli, I Bargagna… - International journal of …, 2022 - mdpi.com
Triple-negative breast cancer (TNBC) is associated with high recurrence rates, high
incidence of distant metastases, and poor overall survival (OS). Taxane and anthracycline …

Roles of miRNA and IncRNA in triple-negative breast cancer

J Xu, K Wu, Q Jia, X Ding - Journal of Zhejiang University-science b, 2020 - Springer
Triple-negative breast cancer (TNBC) is currently the most malignant subtype of breast
cancer without effective targeted therapies, which makes its pathogenesis an important …

MicroRNAs involved in carcinogenesis, prognosis, therapeutic resistance, and applications in human triple-negative breast cancer

L Ding, H Gu, X Xiong, H Ao, J Cao, W Lin, M Yu, J Lin… - Cells, 2019 - mdpi.com
Triple-negative breast cancer (TNBC) is the most aggressive, prevalent, and distinct subtype
of breast cancer characterized by high recurrence rates and poor clinical prognosis, devoid …

MicroRNA-mediated autophagy regulation in cancer therapy: the role in chemoresistance/chemosensitivity

M Ashrafizadeh, A Zarrabi, S Orouei… - European Journal of …, 2021 - Elsevier
Chemoresistance has doubled the effort needed to reach an effective treatment for cancer.
Now, scientists should consider molecular pathways and mechanisms involved in …

Triple negative breast cancer in the era of miRNA

H Sabit, E Cevik, H Tombuloglu, S Abdel-Ghany… - Critical reviews in …, 2021 - Elsevier
The objective of this review is to elucidate the role of miRNAs in triple negative breast cancer
(TNBC). To achieve our goal, we searched databases such as PubMed, ScienceDirect …

The emerging role of miRNA clusters in breast cancer progression

A Kandettu, R Radhakrishnan, S Chakrabarty… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Micro RNAs (miRNAs) are small non-coding RNAs that are essential for regulation of gene
expression of the target genes. Large number of miRNAs are organized into defined units …