This review aims to provide a systemic analysis of the in vivo, as well as subcellular, fate of
polymeric micelles (PMs), starting from the entry of PMs into the body. Few PMs are able to …

Nanomaterials offer unique physical, chemical and biological properties of interest for
medical imaging and therapy. Over the last two decades, there has been an increasing effort …

The impermeable barrier of solid tumors due to the complexity of their components limits the
treatment effect of nanomedicine and hinders its clinical translation. Several methods are …

During the past few decades, polymeric micelles have raised special attention as novel
nano-sized drug delivery systems for optimizing the treatment and diagnosis of numerous …

Micelles are colloidal particles with a size around 5–100 nm which are currently under
investigation as carriers for hydrophobic drugs in anticancer therapy. Currently, five micellar …

Pretargeted nuclear imaging and radiotherapy have recently attracted increasing attention
for diagnosis and treatment of cancer with nanomedicines. This is because it conceptually …

Poly (ɛ-caprolactone)–poly (ethylene glycol)(PCL–PEG) copolymers are important synthetic
biomedical materials with amphiphilicity, controlled biodegradability, and great …

In this study, critical micelle concentration (cmc) was determined for polybutadiene-block-
poly (ethyleneoxide), PB (1800)-b-PEO (4000) amphiphilic diblock copolymer in aqueous …

The current study describes the impact of particle size and/or molecular targeting (epidermal
growth factor, EGF) on the in vivo transport of block copolymer micelles (BCMs) in athymic …

The use of block copolymer micelles (BCMs) for the targeted delivery of chemotherapeutics
has proven to be a promising approach for improving the therapeutic efficacy of …