This report presents the applications of enantioselective epoxidation of prochiral allylic
alcohols, so called 'Sharpless asymmetric epoxidation', which is frequently referred as …

The development of resistance by the antibiotics in the Gram-positive pathogenic bacteria
over the last twenty years and continuing today has created a need for new antibiotic …

Emphasizing the impact of metathesis in natural product synthesis through the different
types of key reactions, this is a comprehensive view of a hot topic. Written by top …

A simple, one-pot method for the α-acyloxylation of carbonyl compounds that proceeds at
room temperature in the presence of both moisture and air has been developed. Treatment …

The synthesis of enantiopure epoxides, as well as their corresponding vicinal diols is an
actively pursued area of research. This is due to the fact that these compounds are essential …

The initiation, growth, and development of new blood vessels through angiogenesis are
essential for tumor growth. Tumor masses require access to blood vessels for a sufficient …

The synthesis of the novel squalene synthase inhibitor, bisabosqual A, was completed in 14
steps (longest linear sequence) from commercially available starting materials. The doubly …

Background: Fungi are a well-known and valuable source of compounds of therapeutic
relevance, in particular of novel anticancer compounds. Although seldom obtainable …

The preparation of a series of new fumagillin-derived MetAP-2 inhibitors is described. The
synthetic approach was designed so as to permit modification of the fumagillin backbone at …

The inhibition of angiogenesis is a promising method of treating diseases in which this
process is involved, such as cancer and rheumatoid arthritis.[1] During our continuing …