Current advances in digital cognitive assessment for preclinical Alzheimer's disease
There is a pressing need to capture and track subtle cognitive change at the preclinical
stage of Alzheimer's disease (AD) rapidly, cost‐effectively, and with high sensitivity …
stage of Alzheimer's disease (AD) rapidly, cost‐effectively, and with high sensitivity …
[HTML][HTML] Cognitive impairment and decline in cognitively normal older adults with high amyloid-β: a meta-analysis
Introduction This meta-analysis aimed to characterize the nature and magnitude of amyloid
(Aβ)-related cognitive impairment and decline in cognitively normal (CN) older individuals …
(Aβ)-related cognitive impairment and decline in cognitively normal (CN) older individuals …
Association of cerebral amyloid-β aggregation with cognitive functioning in persons without dementia
Importance Cerebral amyloid-β aggregation is an early event in Alzheimer disease (AD).
Understanding the association between amyloid aggregation and cognitive manifestation in …
Understanding the association between amyloid aggregation and cognitive manifestation in …
Current state of self-administered brief computerized cognitive assessments for detection of cognitive disorders in older adults: a systematic review
E Tsoy, S Zygouris, KL Possin - The journal of prevention of Alzheimer's …, 2021 - Springer
Early diagnosis of cognitive disorders in older adults is a major healthcare priority with
benefits to patients, families, and health systems. Rapid advances in digital technology offer …
benefits to patients, families, and health systems. Rapid advances in digital technology offer …
Association of β-amyloid accumulation with executive function in adults with unimpaired cognition
P Tideman, E Stomrud, A Leuzy, N Mattsson-Carlgren… - Neurology, 2022 - AAN Enterprises
Background and Objectives The neuropathologic changes underlying Alzheimer disease
(AD) start before overt cognitive symptoms arise, but it is not well-known how they relate to …
(AD) start before overt cognitive symptoms arise, but it is not well-known how they relate to …
The contribution of genetic factors to cognitive impairment and dementia: Apolipoprotein E gene, gene interactions, and polygenic risk
J Fan, W Tao, X Li, H Li, J Zhang, D Wei… - International journal of …, 2019 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease. Although it has been
studied for years, the pathogenesis of AD is still controversial. Genetic factors may play an …
studied for years, the pathogenesis of AD is still controversial. Genetic factors may play an …
[HTML][HTML] Plasma amyloid is associated with the rate of cognitive decline in cognitively normal elderly: the SCIENCe project
IMW Verberk, HMA Hendriksen, AC van Harten… - Neurobiology of …, 2020 - Elsevier
Plasma biomarkers are promising prognostic tools in individuals with subjective cognitive
decline (SCD). We aimed to investigate the relationships of baseline plasma amyloid beta …
decline (SCD). We aimed to investigate the relationships of baseline plasma amyloid beta …
[HTML][HTML] Amyloid PET and cognitive decline in cognitively normal individuals: the SCIENCe project
T Timmers, R Ossenkoppele, SCJ Verfaillie… - Neurobiology of …, 2019 - Elsevier
We examined the relationships between amyloid-β PET and concurrent and longitudinal
cognitive performance in 107 cognitively normal individuals with subjective cognitive decline …
cognitive performance in 107 cognitively normal individuals with subjective cognitive decline …
Associations between performance on an abbreviated CogState battery, other measures of cognitive function, and biomarkers in people at risk for Alzheimer's disease
AM Racine, LR Clark, SE Berman… - Journal of …, 2016 - content.iospress.com
It is not known whether computerized cognitive assessments, like the CogState battery, are
sensitive to preclinical cognitive changes or pathology in people at risk for Alzheimer's …
sensitive to preclinical cognitive changes or pathology in people at risk for Alzheimer's …
Longitudinal comparison of in clinic and at home administration of the cogstate brief battery and demonstrated practice effects in the Mayo Clinic Study of Aging
NH Stricker, ES Lundt, EC Alden, SM Albertson… - The journal of …, 2020 - Springer
Abstract Background The Cogstate Brief Battery (CBB) is a computerized cognitive
assessment that can be completed in clinic or at home. Design/Objective This retrospective …
assessment that can be completed in clinic or at home. Design/Objective This retrospective …