On the translocation of bacteria and their lipopolysaccharides between blood and peripheral locations in chronic, inflammatory diseases: the central roles of LPS and …
DB Kell, E Pretorius - Integrative Biology, 2015 - academic.oup.com
We have recently highlighted (and added to) the considerable evidence that blood can
contain dormant bacteria. By definition, such bacteria may be resuscitated (and thus …
contain dormant bacteria. By definition, such bacteria may be resuscitated (and thus …
Maintaining a protective state for human periodontal tissue
M Yamamoto, R Aizawa - Periodontology 2000, 2021 - Wiley Online Library
Periodontitis, caused by infection with periodontal pathogens, is primarily characterized by
inflammatory bone resorption and destruction of connective tissue. Simply describing …
inflammatory bone resorption and destruction of connective tissue. Simply describing …
Method for diagnosing, preventing, and treating neurological diseases
SM Finegold - US Patent 9,707,207, 2017 - Google Patents
The invention provides for methods of treating autism associated with Desulfovibrio
overgrowth in the gastroin testinal tract of a patient, said method comprising adminis tering …
overgrowth in the gastroin testinal tract of a patient, said method comprising adminis tering …
A nanotrap improves survival in severe sepsis by attenuating hyperinflammation
Targeting single mediators has failed to reduce the mortality of sepsis. We developed a
telodendrimer (TD) nanotrap (NT) to capture various biomolecules via multivalent, hybrid …
telodendrimer (TD) nanotrap (NT) to capture various biomolecules via multivalent, hybrid …
Defensins and LL‐37: a review of function in the gingival epithelium
A Greer, C Zenobia, RP Darveau - Periodontology 2000, 2013 - Wiley Online Library
Antimicrobial peptides represent an important aspect of the innate defense system that
contributes to the control of bacterial colonization and infection. As studies have progressed …
contributes to the control of bacterial colonization and infection. As studies have progressed …
Host defense (antimicrobial) peptides
E Sun, CR Belanger, EF Haney… - Peptide applications in …, 2018 - Elsevier
Small cationic, amphipathic peptides with critical roles in host defenses often exhibit
overlapping but distinct immunomodulatory activity, direct antimicrobial activity towards …
overlapping but distinct immunomodulatory activity, direct antimicrobial activity towards …
Synergistic anti-inflammatory activity of the antimicrobial peptides human beta-defensin-3 (hBD-3) and cathelicidin (LL-37) in a three-dimensional co-culture model of …
TBL Bedran, MPA Mayer, DP Spolidorio, D Grenier - PloS one, 2014 - journals.plos.org
Given the spread of antibiotic resistance in bacterial pathogens, antimicrobial peptides that
can also modulate the immune response may be a novel approach for effectively controlling …
can also modulate the immune response may be a novel approach for effectively controlling …
Antibacterial and detoxifying activity of NZ17074 analogues with multi-layers of selective antimicrobial actions against Escherichia coli and Salmonella enteritidis
N Yang, X Liu, D Teng, Z Li, X Wang, R Mao… - Scientific Reports, 2017 - nature.com
Abstract NZ17074 (N1), an arenicin-3 derivative isolated from the lugworm, has potent
antibacterial activity and is cytotoxic. To reduce its cytotoxicity, seven N1 analogues with …
antibacterial activity and is cytotoxic. To reduce its cytotoxicity, seven N1 analogues with …
Serum vitamin D concentration is associated with antimicrobial peptide level in periodontal diseases
BA Bayirli, A Öztürk, B Avci - Archives of Oral Biology, 2020 - Elsevier
Objective The aim of the study was to assess whether or not Vitamin D deficiency was
associated with the GCF and gingival tissue antimicrobial peptides (AMP), namely, human …
associated with the GCF and gingival tissue antimicrobial peptides (AMP), namely, human …
Regulation of macrophage cell surface GAPDH alters LL-37 internalization and downstream effects in the cell
A Dhiman, S Talukdar, GK Chaubey… - Journal of Innate …, 2023 - karger.com
Abstract Mycobacterium tuberculosis (M. tb), the major causative agent of tuberculosis, has
evolved mechanisms to evade host defenses and persist within host cells. Host-directed …
evolved mechanisms to evade host defenses and persist within host cells. Host-directed …