Despite development in the understanding of the pathogenesis of acute lung injury
(ALI)/acute respiratory distress syndrome (ARDS), the underlying mechanism still needs to …

The acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in
critically ill patients and is defined by the acute onset of noncardiogenic pulmonary oedema …

Obesity alters adipose tissue metabolic and endocrine function and leads to an increased
release of fatty acids, hormones, and proinflammatory molecules that contribute to obesity …

Phagocytes such as neutrophils and macrophages produce reactive oxygen species (ROS)
during phagocytosis or stimulation with a wide variety of agents through activation of …

Recent in vivo and in vitro work suggests that mesenchymal stem cells (MSC) have anti-
inflammatory properties. In this study, we tested the effect of administering MSC directly into …

Background Microvesicles (MVs) are important mediators of intercellular communication,
packaging a variety of molecular cargo. They have been implicated in the pathophysiology …

Although the antibody-based recognition of cell-surface markers has been widely used for
the identification of immune cells, overlap in the expression of markers by different cell types …

The World Health Organization estimates that lower respiratory tract infections (excluding
tuberculosis) account for∼ 35% of all deaths caused by infectious diseases. In many cases …

Mechanical ventilation generates injurious forces that exacerbate lung injury. These forces
disrupt lung barrier integrity, trigger proinflammatory mediator release, and differentially …

Acute lung injury (ALI) and its more severe form acute respiratory distress syndrome (ARDS)
are life-threatening diseases that are characterized by acute onset, pulmonary inflammation …