Current trends in gelatin-based drug delivery systems

F Milano, A Masi, M Madaghiele, A Sannino… - Pharmaceutics, 2023 - mdpi.com
Gelatin is a highly versatile natural polymer, which is widely used in healthcare-related
sectors due to its advantageous properties, such as biocompatibility, biodegradability, low …

Ocular drug delivery: Role of degradable polymeric nanocarriers for ophthalmic application

CH Tsai, PY Wang, IC Lin, H Huang, GS Liu… - International journal of …, 2018 - mdpi.com
Ocular drug delivery has been a major challenge for clinical pharmacologists and
biomaterial scientists due to intricate and unique anatomical and physiological barriers in …

Polymer-based carriers for ophthalmic drug delivery

JC Imperiale, GB Acosta, A Sosnik - Journal of controlled release, 2018 - Elsevier
Despite the wide range of diseases affecting the eye, ocular bioavailability remains a
challenge in ophthalmic drug delivery. Nowadays an extensive variety of polymers are being …

Gelatin as a bioactive nanodelivery system for functional food applications

Y Tan, Y Zi, J Peng, C Shi, Y Zheng, J Zhong - Food Chemistry, 2023 - Elsevier
Gelatin has long been used as an encapsulant agent in the pharmaceutical and biomedical
industries because of its low cost, wide availability, biocompatibility, and degradability …

Exploring the use of nanocarrier systems to deliver the magical molecule; curcumin and its derivatives

M Mehanny, RM Hathout, AS Geneidi… - Journal of controlled …, 2016 - Elsevier
Curcumin and its derivatives; curcuminoids have been proven as potential remedies in
different diseases. However, their delivery carries several challenges owing to their poor …

Thermosensitive chitosan-gelatin-based hydrogel containing curcumin-loaded nanoparticles and latanoprost as a dual-drug delivery system for glaucoma treatment

YH Cheng, YC Ko, YF Chang, SH Huang… - Experimental eye …, 2019 - Elsevier
Elevated intraocular pressure (IOP) in glaucoma is due to impairment of aqueous humor
drainage via the uveoscleral or trabecular outflow pathway. Latanoprost reduces IOP by …

Recent advances in drug delivery systems for glaucoma treatment

KD Patel, LB Silva, Y Park, T Shakouri… - Materials Today …, 2022 - Elsevier
Glaucoma is a chronic eye disease and the second most leading cause of irreversible
impaired vision in the world, which is primarily linked with high intraocular pressure (IOP) …

Biodegradable polymer-based drug-delivery Systems for Ocular Diseases

TH Tsung, YC Tsai, HP Lee, YH Chen… - International Journal of …, 2023 - mdpi.com
Ocular drug delivery is a challenging field due to the unique anatomical and physiological
barriers of the eye. Biodegradable polymers have emerged as promising tools for efficient …

Multifunctional glutathione-dependent hydrogel eye drops with enhanced drug bioavailability for glaucoma therapy

JY Lai, LJ Luo, DD Nguyen - Chemical Engineering Journal, 2020 - Elsevier
The development of drug carriers with advanced functions to overcome the low
bioavailability of conventional eye drops is critical for the effective treatment of chronic ocular …

Thermosensitive chitosan-based hydrogel as a topical ocular drug delivery system of latanoprost for glaucoma treatment

YH Cheng, TH Tsai, YY Jhan, AW Chiu, KL Tsai… - Carbohydrate …, 2016 - Elsevier
Ocular hypertension is a major risk factor for the development and progression of glaucoma.
Frequent and long-term application of latanoprost often causes undesirable local side …