Amorphous solid dispersions (ASDs) are popular for enhancing the solubility and
bioavailability of poorly water-soluble drugs. Various approaches have been employed to …

Background The purpose of this study was to screen various drug delivery systems for
improving the aqueous solubility and oral bioavailability of sildenafil. Three representative …

Aqueous colloidal dispersions of water-insoluble polymers (APDs) avoid hassles associated
with the use of organic solvents and offer processing advantages related to their low …

Purpose Precipitation of amorphous solid dispersions has gained traction in the
pharmaceutical industry given its application to pharmaceuticals with varying …

Near infrared spectroscopy (NIRS) was utilized to determine the endpoint of secondary
drying process (post primary spray drying) of Spray-Dried Intermediates (SDI). In addition …

Apremilast (APST) is an effective inhibitor of phosphodieasterase 4 (PDE4) which is the first
oral drug for the treatment of adult patients with active psoriatic arthritis. However …

Purpose Loss-in-weight feeders play a vital role in assuring blend and content uniformity as
well as lot-to-lot powder traceability in continuous manufacturing. Irregular flow from the …

Although amorphous solid dispersion (ASD) is a promising strategy for enhancing drug
solubility, it has not been recognized to its full potential due to a lack of understanding as to …

A combustão do carvão mineral resulta em dois tipos de resíduos sólidos: cinza volante e
cinza pesada. A cinza volante expelida pela chaminé é constituida de partículas …

Amorphous solid dispersions (ASDs) are popular for enhancing the solubility and
bioavailability of poorly water-soluble drugs. Various approaches have been employed to …