The ability to make decisions and act quickly without hesitation can be advantageous in
many settings. However, when persistently expressed, impulsive decisions and actions are …

Obsessive compulsive disorder (OCD) and attention deficit hyperactivity disorder (ADHD)
are two of the most common neuropsychiatric diseases in paediatric populations. The high …

Abstract Catechol-O-methyltransferase (COMT) is an enzyme that catalyses the methylation
of catechol substrates, classically in catecholamine metabolism, but also acting upon other …

Impulsive personality traits are heritable risk factors and putative endophenotypes for
addiction and other psychiatric disorders involving disinhibition. This study examined the …

The mechanisms underlying bipolar disorder (BD) and the associated medical burden are
unclear. Damage generated by oxidation of nucleosides may be implicated in BD …

Brain development may be influenced by both genetic and environmental factors, with
potential consequences that may last through the lifespan. Alterations during neurogenesis …

Few studies have assessed the association between attention‐deficit hyperactivity disorder
(ADHD) and eating disorders (ED) separately in men and women, especially in …

Impulsivity is a relevant construct for explaining both normal individual differences in
personality and more extreme personality disorder, and is often investigated within clinical …

Neuropsychological studies of adults with problem gambling indicate impairments across
multiple cognitive domains. Catechol-O-methyltransferase (COMT) plays a unique role in the …

A high number of genome variants are associated with complex traits, mainly due to genome-
wide association studies (GWAS). Using polygenic risk scores (PRSs) is a widely accepted …