The role of caspases in Alzheimer's disease: pathophysiology implications and pharmacologic modulation
MR Khezri… - Journal of Alzheimer's …, 2023 - content.iospress.com
Alzheimer's disease (AD) is the most common neurodegenerative disorder worldwide.
Although the main cause of the onset and development of AD is not known yet, neuronal …
Although the main cause of the onset and development of AD is not known yet, neuronal …
Leflunomide abrogates neuroinflammatory changes in a rat model of Alzheimer's disease: the role of TNF-α/NF-κB/IL-1β axis inhibition
M Nafea, M Elharoun, MM Abd-Alhaseeb… - Naunyn-Schmiedeberg's …, 2023 - Springer
Alzheimer's disease (AD) is one of the most common neurodegenerative diseases and is
associated with disrupted cognition and behavior. Neuroinflammatory pathogenesis is the …
associated with disrupted cognition and behavior. Neuroinflammatory pathogenesis is the …
[HTML][HTML] Drug repurposing for neurodegenerative diseases using Zebrafish behavioral profiles
TDR Hernández, SV Gore, JA Kreiling… - Biomedicine & …, 2024 - Elsevier
Drug repurposing can accelerate drug development while reducing the cost and risk of
toxicity typically associated with de novo drug design. Several disorders lacking …
toxicity typically associated with de novo drug design. Several disorders lacking …
Protection of insect neurons by erythropoietin/CRLF3-mediated regulation of pro-apoptotic acetylcholinesterase
DY Knorr, K Schneider, L Büschgens, J Förster… - Scientific Reports, 2022 - nature.com
Cytokine receptor-like factor 3 (CRLF3) is a conserved but largely uncharacterized orphan
cytokine receptor of eumetazoan animals. CRLF3-mediated neuroprotection in insects can …
cytokine receptor of eumetazoan animals. CRLF3-mediated neuroprotection in insects can …
Neuroprotective efficiency of celecoxib vesicular bilosomes for the management of lipopolysaccharide-induced Alzheimer in mice employing 23 full factorial design
AB Darwish, A Salama, MM Younis - Inflammopharmacology, 2024 - Springer
The aim of this study was to develop and evaluate bilosomes loaded with Celecoxib (CXB)
for the efficient treatment of Alzheimer. The thin-film hydration approach was utilized in the …
for the efficient treatment of Alzheimer. The thin-film hydration approach was utilized in the …
[HTML][HTML] Finding Drug Repurposing Candidates for Neurodegenerative Diseases using Zebrafish Behavioral Profiles
Drug repurposing can accelerate drug development while reducing the cost and risk of
toxicity typically associated with de novo drug design. Several disorders lacking …
toxicity typically associated with de novo drug design. Several disorders lacking …
[PDF][PDF] التأثير الوقائي لبعض الأغذية الغنية بالكولين والسيلينيوم والفلافونويد من الزهايمر في الفئران
رضوى شاهين - المجلة المصرية للدراسات المتخصصة, 2022 - journals.ekb.eg
Background: Choline, selenium and flavonoids are identified as potential antioxidants that
can detoxify different Reactive Oxygen Species (ROS) in neurological diseases. Aim: This …
can detoxify different Reactive Oxygen Species (ROS) in neurological diseases. Aim: This …