[HTML][HTML] Monitoring the neuroinflammatory response following acute brain injury
Traumatic brain injury (TBI) and subarachnoid hemorrhage (SAH) are major contributors to
morbidity and mortality. Following the initial insult, patients may deteriorate due to secondary …
morbidity and mortality. Following the initial insult, patients may deteriorate due to secondary …
[HTML][HTML] Assessing metabolism and injury in acute human traumatic brain injury with magnetic resonance spectroscopy: current and future applications
MG Stovell, JL Yan, A Sleigh, MO Mada… - Frontiers in …, 2017 - frontiersin.org
Traumatic brain injury (TBI) triggers a series of complex pathophysiological processes.
These include abnormalities in brain energy metabolism; consequent to reduced tissue pO2 …
These include abnormalities in brain energy metabolism; consequent to reduced tissue pO2 …
Rapid optofluidic detection of biomarkers for traumatic brain injury via surface-enhanced Raman spectroscopy
Current technologies for the point-of-care diagnosis of traumatic brain injury (TBI) lack
sensitivity, require specialist handling or involve complicated and costly procedures. Here …
sensitivity, require specialist handling or involve complicated and costly procedures. Here …
[HTML][HTML] Longitudinal neuroimaging in pediatric traumatic brain injury: current state and consideration of factors that influence recovery
HM Lindsey, EA Wilde, K Caeyenberghs… - Frontiers in …, 2019 - frontiersin.org
Traumatic brain injury (TBI) is a leading cause of death and disability for children and
adolescents in the US and other developed and developing countries. Injury to the immature …
adolescents in the US and other developed and developing countries. Injury to the immature …
Tracing the path of disruption: 13C isotope applications in traumatic brain injury‐induced metabolic dysfunction
CJ Peper, MD Kilgore, Y Jiang, Y Xiu… - CNS Neuroscience …, 2024 - Wiley Online Library
Cerebral metabolic dysfunction is a critical pathological hallmark observed in the aftermath
of traumatic brain injury (TBI), as extensively documented in clinical investigations and …
of traumatic brain injury (TBI), as extensively documented in clinical investigations and …
[HTML][HTML] Traumatic brain injury induces region-specific glutamate metabolism changes as measured by multiple mass spectrometry methods
JL Sowers, ML Sowers, AS Shavkunov, BE Hawkins… - Iscience, 2021 - cell.com
The release of excess glutamate following traumatic brain injury (TBI) results in glutamate
excitotoxicity and metabolic energy failure. Endogenous mechanisms for reducing glutamate …
excitotoxicity and metabolic energy failure. Endogenous mechanisms for reducing glutamate …
Imaging biomarkers of posttraumatic epileptogenesis
Traumatic brain injury (TBI) affects 2.5 million people annually within the United States
alone, with over 300 000 severe injuries resulting in emergency room visits and hospital …
alone, with over 300 000 severe injuries resulting in emergency room visits and hospital …
Brain metabolites measured with magnetic resonance spectroscopy in pediatric concussion and orthopedic injury: An Advancing Concussion Assessment in …
Millions of children sustain a concussion annually. Concussion disrupts cellular signaling
and neural pathways within the brain but the resulting metabolic disruptions are not well …
and neural pathways within the brain but the resulting metabolic disruptions are not well …
Longitudinal metabolite changes after traumatic brain injury: a prospective pediatric magnetic resonance spectroscopic imaging study
B Holshouser, J Pivonka-Jones, JG Nichols… - Journal of …, 2019 - liebertpub.com
The aims of this study were to evaluate longitudinal metabolite changes in traumatic brain
injury (TBI) subjects and determine whether early magnetic resonance spectroscopic …
injury (TBI) subjects and determine whether early magnetic resonance spectroscopic …
[HTML][HTML] Current opportunities for clinical monitoring of axonal pathology in traumatic brain injury
PP Tsitsopoulos, S Abu Hamdeh, N Marklund - Frontiers in neurology, 2017 - frontiersin.org
Traumatic brain injury (TBI) is a multidimensional and highly complex disease commonly
resulting in widespread injury to axons, due to rapid inertial acceleration/deceleration forces …
resulting in widespread injury to axons, due to rapid inertial acceleration/deceleration forces …