[HTML][HTML] Monitoring the neuroinflammatory response following acute brain injury

EP Thelin, T Tajsic, FA Zeiler, DK Menon… - Frontiers in …, 2017 - frontiersin.org
Traumatic brain injury (TBI) and subarachnoid hemorrhage (SAH) are major contributors to
morbidity and mortality. Following the initial insult, patients may deteriorate due to secondary …

[HTML][HTML] Assessing metabolism and injury in acute human traumatic brain injury with magnetic resonance spectroscopy: current and future applications

MG Stovell, JL Yan, A Sleigh, MO Mada… - Frontiers in …, 2017 - frontiersin.org
Traumatic brain injury (TBI) triggers a series of complex pathophysiological processes.
These include abnormalities in brain energy metabolism; consequent to reduced tissue pO2 …

Rapid optofluidic detection of biomarkers for traumatic brain injury via surface-enhanced Raman spectroscopy

JJS Rickard, V Di-Pietro, DJ Smith, DJ Davies… - Nature biomedical …, 2020 - nature.com
Current technologies for the point-of-care diagnosis of traumatic brain injury (TBI) lack
sensitivity, require specialist handling or involve complicated and costly procedures. Here …

[HTML][HTML] Longitudinal neuroimaging in pediatric traumatic brain injury: current state and consideration of factors that influence recovery

HM Lindsey, EA Wilde, K Caeyenberghs… - Frontiers in …, 2019 - frontiersin.org
Traumatic brain injury (TBI) is a leading cause of death and disability for children and
adolescents in the US and other developed and developing countries. Injury to the immature …

Tracing the path of disruption: 13C isotope applications in traumatic brain injury‐induced metabolic dysfunction

CJ Peper, MD Kilgore, Y Jiang, Y Xiu… - CNS Neuroscience …, 2024 - Wiley Online Library
Cerebral metabolic dysfunction is a critical pathological hallmark observed in the aftermath
of traumatic brain injury (TBI), as extensively documented in clinical investigations and …

[HTML][HTML] Traumatic brain injury induces region-specific glutamate metabolism changes as measured by multiple mass spectrometry methods

JL Sowers, ML Sowers, AS Shavkunov, BE Hawkins… - Iscience, 2021 - cell.com
The release of excess glutamate following traumatic brain injury (TBI) results in glutamate
excitotoxicity and metabolic energy failure. Endogenous mechanisms for reducing glutamate …

Imaging biomarkers of posttraumatic epileptogenesis

R Garner, M La Rocca, P Vespa, N Jones, MM Monti… - …, 2019 - Wiley Online Library
Traumatic brain injury (TBI) affects 2.5 million people annually within the United States
alone, with over 300 000 severe injuries resulting in emergency room visits and hospital …

Brain metabolites measured with magnetic resonance spectroscopy in pediatric concussion and orthopedic injury: An Advancing Concussion Assessment in …

PL La, JM Joyce, TK Bell, M Mauthner… - Human Brain …, 2023 - Wiley Online Library
Millions of children sustain a concussion annually. Concussion disrupts cellular signaling
and neural pathways within the brain but the resulting metabolic disruptions are not well …

Longitudinal metabolite changes after traumatic brain injury: a prospective pediatric magnetic resonance spectroscopic imaging study

B Holshouser, J Pivonka-Jones, JG Nichols… - Journal of …, 2019 - liebertpub.com
The aims of this study were to evaluate longitudinal metabolite changes in traumatic brain
injury (TBI) subjects and determine whether early magnetic resonance spectroscopic …

[HTML][HTML] Current opportunities for clinical monitoring of axonal pathology in traumatic brain injury

PP Tsitsopoulos, S Abu Hamdeh, N Marklund - Frontiers in neurology, 2017 - frontiersin.org
Traumatic brain injury (TBI) is a multidimensional and highly complex disease commonly
resulting in widespread injury to axons, due to rapid inertial acceleration/deceleration forces …