Intervertebral disc degeneration (IDD) is a common cause of joint-related chronic disability
in elderly individuals worldwide. It seriously impacts the quality of life and inflicts a …

Simple Summary Patients with ovarian cancer have a very poor chance of long-term
survival, usually due to advanced disease at the time of diagnosis. Emerging evidence …

The epigenome coordinates spatial-temporal specific gene expression during development
and in adulthood, for the maintenance of homeostasis and upon tissue repair. The upheaval …

Clear cell renal cell carcinoma (ccRCC) are typically situated in a complex inflammatory and
immune microenvironment, which has been reported to contribute to the unfavorable …

The existence of a tight relationship between inflammation and epigenetics that in primary
breast tumor cells can lead to tumor progression and the formation of bone metastases was …

Although anti-programmed death-1 (PD-1) antibody therapy improves the prognosis in
patients with head and neck squamous cell carcinoma (HNSCC), some patients exhibit …

Breast cancer remains a major global health challenge. Its rising incidence is attributed to
factors such as delayed diagnosis, the complexity of its subtypes, and increasing drug …

Brain metastasis (BrM) is a major threat to the survival of melanoma, breast, and lung cancer
patients. Circulating tumor cells (CTCs) cross the blood-brain barrier (BBB) and sustain in …

Inflammation is an essential defense mechanism in which innate immune cells are
coordinately activated on encounter of harmful stimuli, including pathogens, tissue injury …

The SARS-CoV-2 outbreak has infected a vast population across the world, causing more
than 664 million cases and 6.7 million deaths by January 2023. Vaccination has been …